Systems Biology of Monovalent Cation Homeostasis in Yeast. The Translucent Contribution.

Joaquín Ariño, Ebru Aydar, Samuel Drulhe, Daniel Ganser, Jesús Jorrín, Matthias Kahm, Falko Krause, Silvia Petrezsélyová, Lynne Yenush, Olga Zimmermannová, G. Paul H. Van Heusden, Maik Kschischo, Jost Ludwig, Chris Palmer, José Ramos, Hana Sychrová

Research output: Chapter in BookChapterResearchpeer-review

16 Citations (Scopus)

Abstract

Maintenance of monovalent cation homeostasis (mainly K+ and Na+) is vital for cell survival, and cation toxicity is at the basis of a myriad of relevant phenomena, such as salt stress in crops and diverse human diseases. Full understanding of the importance of monovalent cations in the biology of the cell can only be achieved from a systemic perspective. Translucent is a multinational project developed within the context of the SysMO (System Biology of Microorganisms) initiative and focussed in the study of cation homeostasis using the well-known yeast Saccharomyces cerevisiae as a model. The present review summarize how the combination of biochemical, genetic, genomic and computational approaches has boosted our knowledge in this field, providing the basis for a more comprehensive and coherent vision of the role of monovalent cations in the biology of the cell. © 2014 Elsevier Ltd.
Original languageEnglish
Title of host publicationAdvances in Microbial Physiology
Pages1-63
Number of pages62
Volume64
DOIs
Publication statusPublished - 1 Jan 2014

Keywords

  • Cation transport
  • Potassium homeostasis
  • Saccharomyces cerevisiae
  • Salt stress
  • Systems biology

Fingerprint

Dive into the research topics of 'Systems Biology of Monovalent Cation Homeostasis in Yeast. The Translucent Contribution.'. Together they form a unique fingerprint.

Cite this