Background: A disease resembling feline infectious peritonitis (FIP) has been recognized recently in ferrets, mostly in United States and in Spain. This disease is due to a Group 1 Coronavirus, closely related to the ferret enteric Coronavirus. Objective: To demonstrate the viral origin of severe pyogranulomatous lymphoid and visceral lesions in three ferrets. Methods: Histopathology and immunohistochemistry of lesions received in our laboratory. Results: Severe pyogranulomatous inflammation was observed in the abdominal lymph nodes and in various organs. Positive labelling of Coronavirus antigen was demonstrated in macrophages in the pyogranulomatous lesions by immunohistochemistry. Conclusion: The three cases of severe pyogranulomatous disseminated inflammation were due to a Coronavirus, causing a systemic coronavirosis in ferret with a high similarity to FIP. © 2009 AFVAC.
|Journal||Pratique Medicale et Chirurgicale de l'Animal de Compagnie|
|Publication status||Published - 1 Oct 2009|
- Feline coronavirosis
Laprie, C., Duboy, J., & Martinez, J. (2009). Systemic Coronavirus-associated disease in the domestic ferret (Mustela putorius): Histopathologic and immunohistochemical characterization in three ferrets. Pratique Medicale et Chirurgicale de l'Animal de Compagnie, 44(4), 111-115. https://doi.org/10.1016/j.anicom.2009.07.004