Abstract
Several title compounds were synthesized according to new methods based either on the use of D-ribonolactone as a chiral precursor or on the cyclization of 2,4-dioxopentanoic acid as a suitable achiral precursor. Base-induced elimination and subsequent acid-promoted ring contraction is an efficient protocol for the preparation of isotetronic acids from 2-O-alkyl-3,4-O-benzylidene-D-ribono-1,5-lactone derivatives. © 1993.
Original language | English |
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Pages (from-to) | 6717-6728 |
Journal | Tetrahedron |
Volume | 49 |
Issue number | 30 |
DOIs | |
Publication status | Published - 23 Jul 1993 |