Abstract
(matrix presented) The new cyclopropyl carbocyclic nucleosides 1 and 2 have been synthesized by following short and efficient routes starting from conveniently protected (-)-(Z)-methanohomoserine derivative 3. Both products 1 and 2 bear a quaternary stereogenic center and have opposite chirality. Moreover, the adenine derivative 2 belongs to a new class of cyclopropyl nucleoside showing an amino alcohol function at C-1 in addition to a methylene spacer between the base and the carbocyclic ring.
| Original language | English |
|---|---|
| Pages (from-to) | 1221-1223 |
| Journal | Organic Letters |
| Volume | 1 |
| Issue number | 8 |
| Publication status | Published - 21 Oct 1999 |