The synthesis of new N-(4-pyridyl)-1-aminopyrazoles is described. Their binding properties were tested for muscarinic and other neurotransmitter receptors, together with their acetylcholinesterase inhibitory activity. The series derived from 3,5-dimethyl-1H-pyrazole showed moderate activities in both muscarinic and adrenergic receptor binding tests.
|Journal||Archiv der Pharmazie|
|Publication status||Published - 1 May 2000|
- Adrenergic properties
- Alzheimer's disease
- Muscarinic properties