The synthesis of new N-(4-pyridyl)-1-aminopyrazoles is described. Their binding properties were tested for muscarinic and other neurotransmitter receptors, together with their acetylcholinesterase inhibitory activity. The series derived from 3,5-dimethyl-1H-pyrazole showed moderate activities in both muscarinic and adrenergic receptor binding tests.
|Journal||Archiv der Pharmazie|
|Publication status||Published - 1 May 2000|
- Adrenergic properties
- Alzheimer's disease
- Muscarinic properties
Rodríguez-Franco, M. I., Dorronsoro, I., Martínez, A., Pérez, C., Badía, A., & Baños, J. E. (2000). Synthesis of new N-(4-pyridyl)-1-aminopyrazoles and their muscarinic and adrenergic properties. Archiv der Pharmazie, 333(5), 118-122. https://doi.org/10.1002/(SICI)1521-4184(20005)333:5<118::AID-ARDP118>3.0.CO;2-Q