Synthesis of new N-(4-pyridyl)-1-aminopyrazoles and their muscarinic and adrenergic properties

María Isabel Rodríguez-Franco, Isabel Dorronsoro, Ana Martínez, Concepción Pérez, Albert Badía, Josep E. Baños

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)

Abstract

The synthesis of new N-(4-pyridyl)-1-aminopyrazoles is described. Their binding properties were tested for muscarinic and other neurotransmitter receptors, together with their acetylcholinesterase inhibitory activity. The series derived from 3,5-dimethyl-1H-pyrazole showed moderate activities in both muscarinic and adrenergic receptor binding tests.
Original languageEnglish
Pages (from-to)118-122
JournalArchiv der Pharmazie
Volume333
Issue number5
DOIs
Publication statusPublished - 1 May 2000

Keywords

  • 1-Aminopyrazoles
  • 4-aminopyridines
  • Adrenergic properties
  • Alzheimer's disease
  • Muscarinic properties

Fingerprint Dive into the research topics of 'Synthesis of new N-(4-pyridyl)-1-aminopyrazoles and their muscarinic and adrenergic properties'. Together they form a unique fingerprint.

  • Cite this