Synthesis of (+)-methyl (R, E)-6-benzyloxy-4-hydroxy-2-hexenoate and its mesylate derivative

Pedro de March, Marta Figueredo, Josep Font, Montserrat Monsalvatje

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Abstract

Methyl (E)-6-benzyloxy-4-hydroxy-2-hexenoate is prepared in both racemic and enantiopure form through reaction between (2-benzyloxy)ethyloxirane and the dianion of phenylselenoacetic acid followed by esterification with diazomethane, oxidation to the selenoxide and subsequent pyrolysis in 72% overall yield. © 1995, Taylor & Francis Group, LLC. All rights reserved.
Original languageEnglish
Pages (from-to)331-342
JournalSynthetic Communications
Volume25
Issue number3
DOIs
Publication statusPublished - 1 Feb 1995

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