© 2018 Georg Thieme Verlag KG Stuttgart · New York. The synthesis of the chiral sulfide isothiocineole from limonene and elemental sulfur on multi-gram scale and its alkylation to make >50 g of the corresponding benzylsulfonium salt are described. The application of this salt to the sulfur ylide-mediated asymmetric epoxidation of aldehydes and the asymmetric aziridination of imines on a >5 g scale is demonstrated.
|Publication status||Published - 1 Jan 2018|
- asymmetric aziridination
- asymmetric epoxidation
- chiral sulfide
- sulfur ylide