Synthesis of chiral cyclobutane containing C3-symmetric peptide dendrimers

Raquel Gutiérrez-Abad, Ona Illa, Rosa M. Ortuño

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25 Citations (Scopus)

Abstract

(Figure Presented) Five new highly functionalized cyclobutane containing C3-symmetric peptide dendrimers have been synthesized through a convergent approach from 1,3,5-trisubstituted benzene and chiral λ,ε-amino diacid derivatives as well as a λ-tetrapeptide. The first example of the synthesis of N-centered amides by using 1,3,5-triaminobenzene and a carboxylic acid is reported. © 2010 American Chemical Society.
Original languageEnglish
Pages (from-to)3148-3151
JournalOrganic Letters
Volume12
Issue number14
DOIs
Publication statusPublished - 16 Jul 2010

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