Synthesis, high-resolution NMR spectroscopic analysis, and single-crystal X-ray diffraction of isoxazoline tetracycles

Mirta L. Fascio; Angel Alvarez-Larena; Norma B. D'Accorso

doi:10.1016/S0008-6215(02)00258-6

Synthesis, high-resolution NMR spectroscopic analysis, and single-crystal X-ray diffraction of isoxazoline tetracycles

Mirta L. Fascio, Angel Alvarez-Larena, Norma B. D'Accorso

Research output: Contribution to journal › Article › Research › peer-review

4 Citations (Scopus)

Abstract

Three isoxazoline tetracycles were obtained enantiomerically pure by intramolecular 1,3-dipolar cycloaddition. The characterization of the new compounds was performed by high-resolution 1H and 13C NMR spectroscopy. The relative configuration of the new chiral centers was determined by NOESY experiments and confirmed by single-crystal X-ray structural analysis. © 2002 Elsevier Science Ltd. All rights reserved.

Original language	English
Pages (from-to)	2419-2425
Journal	Carbohydrate Research
Volume	337
Issue number	24
DOIs	https://doi.org/10.1016/S0008-6215(02)00258-6
Publication status	Published - 29 Nov 2002

Keywords

Intramolecular 1,3-dipolar cycloaddition
Isoxazolines
Stereocontrol, NMR spectroscopy
X-Ray crystallography

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10.1016/S0008-6215(02)00258-6

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title = "Synthesis, high-resolution NMR spectroscopic analysis, and single-crystal X-ray diffraction of isoxazoline tetracycles",

abstract = "Three isoxazoline tetracycles were obtained enantiomerically pure by intramolecular 1,3-dipolar cycloaddition. The characterization of the new compounds was performed by high-resolution 1H and 13C NMR spectroscopy. The relative configuration of the new chiral centers was determined by NOESY experiments and confirmed by single-crystal X-ray structural analysis. {\textcopyright} 2002 Elsevier Science Ltd. All rights reserved.",

keywords = "Intramolecular 1,3-dipolar cycloaddition, Isoxazolines, Stereocontrol, NMR spectroscopy, X-Ray crystallography",

author = "Fascio, {Mirta L.} and Angel Alvarez-Larena and D'Accorso, {Norma B.}",

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T1 - Synthesis, high-resolution NMR spectroscopic analysis, and single-crystal X-ray diffraction of isoxazoline tetracycles

AU - Fascio, Mirta L.

AU - Alvarez-Larena, Angel

AU - D'Accorso, Norma B.

PY - 2002/11/29

Y1 - 2002/11/29

N2 - Three isoxazoline tetracycles were obtained enantiomerically pure by intramolecular 1,3-dipolar cycloaddition. The characterization of the new compounds was performed by high-resolution 1H and 13C NMR spectroscopy. The relative configuration of the new chiral centers was determined by NOESY experiments and confirmed by single-crystal X-ray structural analysis. © 2002 Elsevier Science Ltd. All rights reserved.

AB - Three isoxazoline tetracycles were obtained enantiomerically pure by intramolecular 1,3-dipolar cycloaddition. The characterization of the new compounds was performed by high-resolution 1H and 13C NMR spectroscopy. The relative configuration of the new chiral centers was determined by NOESY experiments and confirmed by single-crystal X-ray structural analysis. © 2002 Elsevier Science Ltd. All rights reserved.

KW - Intramolecular 1,3-dipolar cycloaddition

KW - Isoxazolines

KW - Stereocontrol, NMR spectroscopy

KW - X-Ray crystallography

U2 - 10.1016/S0008-6215(02)00258-6

DO - 10.1016/S0008-6215(02)00258-6

M3 - Article

SN - 0008-6215

VL - 337

SP - 2419

EP - 2425

JO - Carbohydrate Research

JF - Carbohydrate Research

IS - 24

ER -

Synthesis, high-resolution NMR spectroscopic analysis, and single-crystal X-ray diffraction of isoxazoline tetracycles

Abstract

Keywords

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