Three isoxazoline tetracycles were obtained enantiomerically pure by intramolecular 1,3-dipolar cycloaddition. The characterization of the new compounds was performed by high-resolution 1H and 13C NMR spectroscopy. The relative configuration of the new chiral centers was determined by NOESY experiments and confirmed by single-crystal X-ray structural analysis. © 2002 Elsevier Science Ltd. All rights reserved.
|Publication status||Published - 29 Nov 2002|
- Intramolecular 1,3-dipolar cycloaddition
- Stereocontrol, NMR spectroscopy
- X-Ray crystallography