A new (SS)(P) coordination set based on the concurrent use of a dithiocarbamate and a functionalised phosphane is reported. The (SS)(P) fashion is achieved by applying the [2+1] mixed-ligand concept and makes it possible to obtain stable rhenium tricarbonyl complexes without employing tripodal bifunctional chelating agents (BFCAs). The coordination chemistry of the simple sodium N,N-dimethyldithiocarbamate and new functionalised phosphanes L1-L3 [L1 = Ph2PCH2CH2C(O)OCH3, L2 = Ph 2PCH2CH2C(O)NHCH2C(O)OCH 3, L3 = Ph2PCH2CH2C(O)NHCH 2CH2C(O)OCH3] was studied by reaction with the rhenium complex [NEt4]2-[fac-Re(CO3)Br 3]. The rhenium tricarbonyl core was found to be stabilised by the SS chelation of dithiocarbamate and by the P coordination of the phosphane. Two synthetic pathways leading to the complexes [fac-Re(CO)3(L)(MDTC)] (L = L1, L2, L3; MDTC = N,N-dimethyldithiocarbamate) are described. The structural characterisation of the isolated complexes by spectroscopic methods is reported, including X-ray crystallographic analysis for rhenium complexes with ligands L1 and L3. The homologous Tc-99m compounds with the same (SS)(P) coordination set were prepared at tracer level with the L2 and L3 ligands, and characterised by HPLC methods. © Wiley-VCH Verlag GmbH & Co. KGaA, 2005.
|Journal||European Journal of Inorganic Chemistry|
|Publication status||Published - 21 Oct 2005|
- Carbonyl ligands
- P ligands
- S ligands