A new enantiopure cyclic nitrone has been efficiently synthesized from a D-glyceraldehyde derivative. Its 1,3-dipolar cycloaddition to different classes of dipolarophiles show complete antifacial selectivity, furnishing highly functionalized enantiopure bicyclic isoxazolidines. © 2002 Elsevier Science Ltd. All rights reserved.
|Publication status||Published - 13 Jan 2003|
- Dipolar cycloaddition
- Enantiopure cyclic nitrone
- Facial selectivity