Synergistic Exploitation of the Superoxide Scavenger Properties of Reduced Graphene Oxide and a Trityl Organic Radical for the Impedimetric Sensing of Xanthine

Gonca Seber; Jose Muñoz; Stefania Sandoval; Concepció Rovira; Gerard Tobias; Marta Mas-Torrent; Núria Crivillers

doi:10.1002/admi.201701072

Synergistic Exploitation of the Superoxide Scavenger Properties of Reduced Graphene Oxide and a Trityl Organic Radical for the Impedimetric Sensing of Xanthine

Gonca Seber, Jose Muñoz, Stefania Sandoval, Concepció Rovira, Gerard Tobias, Marta Mas-Torrent, Núria Crivillers

Research output: Contribution to journal › Article › Research › peer-review

5 Citations (Scopus)

Abstract

© 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim This work is based on synergetically exploiting the activity of graphene-based materials and trityl free radicals to sense xanthine (X) by their combined scavenging properties for superoxide anion radical (O2•−). For this, reduced graphene oxide (rGO) and rGO covalently functionalized with a perchlorotriphenylmethyl (PTM) radical derivative (rGO@PTM) are synthesized, characterized, and casted on an electrode surface to achieve a highly sensitive electrochemical recognition platform for xanthine determination. The electrochemical analysis is based on impedimetrically monitoring a radical-involved reaction on the graphene-based electrode surface after reacting with such O2•− derived from the xanthine/xanthine oxidase enzymatic system. The presented strategy yields to determine X at nm levels, decreasing the detection limit 100 times with respect to previously reported (bio)sensors.

Original language	English
Article number	1701072
Journal	Advanced Materials Interfaces
Volume	5
Issue number	2
DOIs	https://doi.org/10.1002/admi.201701072
Publication status	Published - 23 Jan 2018

Keywords

reduced graphene oxide
superoxide anion radical
trityl radical
xanthine sensor

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title = "Synergistic Exploitation of the Superoxide Scavenger Properties of Reduced Graphene Oxide and a Trityl Organic Radical for the Impedimetric Sensing of Xanthine",

abstract = "{\textcopyright} 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim This work is based on synergetically exploiting the activity of graphene-based materials and trityl free radicals to sense xanthine (X) by their combined scavenging properties for superoxide anion radical (O2•−). For this, reduced graphene oxide (rGO) and rGO covalently functionalized with a perchlorotriphenylmethyl (PTM) radical derivative (rGO@PTM) are synthesized, characterized, and casted on an electrode surface to achieve a highly sensitive electrochemical recognition platform for xanthine determination. The electrochemical analysis is based on impedimetrically monitoring a radical-involved reaction on the graphene-based electrode surface after reacting with such O2•− derived from the xanthine/xanthine oxidase enzymatic system. The presented strategy yields to determine X at nm levels, decreasing the detection limit 100 times with respect to previously reported (bio)sensors.",

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author = "Gonca Seber and Jose Mu{\~n}oz and Stefania Sandoval and Concepci{\'o} Rovira and Gerard Tobias and Marta Mas-Torrent and N{\'u}ria Crivillers",

year = "2018",

month = jan,

day = "23",

doi = "10.1002/admi.201701072",

language = "English",

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Synergistic Exploitation of the Superoxide Scavenger Properties of Reduced Graphene Oxide and a Trityl Organic Radical for the Impedimetric Sensing of Xanthine. / Seber, Gonca; Muñoz, Jose; Sandoval, Stefania; Rovira, Concepció; Tobias, Gerard; Mas-Torrent, Marta; Crivillers, Núria.

In: Advanced Materials Interfaces, Vol. 5, No. 2, 1701072, 23.01.2018.

Research output: Contribution to journal › Article › Research › peer-review

TY - JOUR

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AU - Seber, Gonca

AU - Muñoz, Jose

AU - Sandoval, Stefania

AU - Rovira, Concepció

AU - Tobias, Gerard

AU - Mas-Torrent, Marta

AU - Crivillers, Núria

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AB - © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim This work is based on synergetically exploiting the activity of graphene-based materials and trityl free radicals to sense xanthine (X) by their combined scavenging properties for superoxide anion radical (O2•−). For this, reduced graphene oxide (rGO) and rGO covalently functionalized with a perchlorotriphenylmethyl (PTM) radical derivative (rGO@PTM) are synthesized, characterized, and casted on an electrode surface to achieve a highly sensitive electrochemical recognition platform for xanthine determination. The electrochemical analysis is based on impedimetrically monitoring a radical-involved reaction on the graphene-based electrode surface after reacting with such O2•− derived from the xanthine/xanthine oxidase enzymatic system. The presented strategy yields to determine X at nm levels, decreasing the detection limit 100 times with respect to previously reported (bio)sensors.

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