Sutureless Valve in Repeated Aortic Valve Replacement: Results from an International Prospective Registry

Mattia Glauber, William D.T. Kent, George Asimakopoulos, Giovanni Troise, Josep Maria Padrò, Alistair Royse, Jean Marc Marnette, Philippe Noirhomme, Max Baghai, Michael Lewis, Lorenzo Di Bacco, Marco Solinas, Antonio Miceli*

*Corresponding author for this work

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)


Objective: To report early and midterm results registry of patients undergoing repeated aortic valve replacement (RAVR) with sutureless prostheses from an international prospective registry (SURE-AVR). Methods: Between March 2011 and June 2019, 69 patients underwent RAVR with self-expandable sutureless aortic bioprostheses at 22 international cardiac centers. Results: Overall mortality was 2.9% with a predicted logistic EuroSCORE II of 10.7%. Indications for RAVR were structural valve dysfunction (84.1%) and infective prosthetic endocarditis (15.9%) and were performed in patients with previously implanted bioprostheses (79.7%), mechanical valves (15.9%), and transcatheter valves (4.3%). Minimally invasive approach was performed in 15.9% of patients. Rate of stroke was 1.4% and rate of early valve-related reintervention was 1.4%. Overall survival rate at 1 and 5 years was 97% and 91%, respectively. No major paravalvular leak occurred. Rate of pacemaker implantation was 5.8% and 0.9% per patient-year early and at follow-up, respectively. The mean transvalvular gradient at 1-year and 5-year follow-up was 10.5 mm Hg and 11.5 mm Hg with a median effective orifice area of 1.8 cm2and 1.8 cm2, respectively. Conclusions: RAVR with sutureless valves is a safe and effective approach and provides excellent clinical and hemodynamic results up to 5 years.

Original languageEnglish
Pages (from-to)273-279
Number of pages7
JournalInnovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
Issue number3
Publication statusPublished - 18 Apr 2021


  • AVR
  • redo surgery
  • sutureless


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