Study of the Stability of Creatine Kinase in Control Materials

Francesca Canalias; Yolanda Saco; F. Javier Gella

doi:https://doi.org/10.1515/cclm.1995.33.9.589

Study of the Stability of Creatine Kinase in Control Materials

Francesca Canalias, Yolanda Saco, F. Javier Gella

Research output: Contribution to journal › Article › Research › peer-review

2 Citations (Scopus)

Abstract

We examined the stability of twelve control materials from different suppliers containing creatine kinase. The stability was assessed storing preparations at 4 °C, 27 °C and 37 °C and periodically measuring creatine kinase catalytic concentration. The activity was significantly greater when the lyophilized material was reconstituted with water at 4 °C as compared to 27 °C and 37 °C. All preparations tested showed good stability at 4 °C over a 72 hour period. We considered the suitability of tested control materials for quality-control purposes. © 1995, Walter de Gruyter. All rights reserved.

Original language	English
Pages (from-to)	589-594
Journal	Clinical Chemistry and Laboratory Medicine
Volume	33
DOIs	https://doi.org/10.1515/cclm.1995.33.9.589
Publication status	Published - 1 Jan 1995

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abstract = "We examined the stability of twelve control materials from different suppliers containing creatine kinase. The stability was assessed storing preparations at 4 °C, 27 °C and 37 °C and periodically measuring creatine kinase catalytic concentration. The activity was significantly greater when the lyophilized material was reconstituted with water at 4 °C as compared to 27 °C and 37 °C. All preparations tested showed good stability at 4 °C over a 72 hour period. We considered the suitability of tested control materials for quality-control purposes. {\textcopyright} 1995, Walter de Gruyter. All rights reserved.",

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AU - Saco, Yolanda

AU - Gella, F. Javier

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N2 - We examined the stability of twelve control materials from different suppliers containing creatine kinase. The stability was assessed storing preparations at 4 °C, 27 °C and 37 °C and periodically measuring creatine kinase catalytic concentration. The activity was significantly greater when the lyophilized material was reconstituted with water at 4 °C as compared to 27 °C and 37 °C. All preparations tested showed good stability at 4 °C over a 72 hour period. We considered the suitability of tested control materials for quality-control purposes. © 1995, Walter de Gruyter. All rights reserved.

AB - We examined the stability of twelve control materials from different suppliers containing creatine kinase. The stability was assessed storing preparations at 4 °C, 27 °C and 37 °C and periodically measuring creatine kinase catalytic concentration. The activity was significantly greater when the lyophilized material was reconstituted with water at 4 °C as compared to 27 °C and 37 °C. All preparations tested showed good stability at 4 °C over a 72 hour period. We considered the suitability of tested control materials for quality-control purposes. © 1995, Walter de Gruyter. All rights reserved.

U2 - https://doi.org/10.1515/cclm.1995.33.9.589

DO - https://doi.org/10.1515/cclm.1995.33.9.589

M3 - Article

VL - 33

SP - 589

EP - 594

JO - Clinical Chemistry and Laboratory Medicine

JF - Clinical Chemistry and Laboratory Medicine

SN - 1434-6621

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