Study of the benefit of an exercise programme and branched amino acid supplements in patients with liver cirrhosis

G. Soriano; E. Román; M. T. Torrades; G. Cárdenas; J. Córdoba; M. J. Nadal; J. C. Nieto; S. Vidal; C. Villanueva; H. Bascuñana; C. Juárez; C. Guarner

Study of the benefit of an exercise programme and branched amino acid supplements in patients with liver cirrhosis

G. Soriano, E. Román, M. T. Torrades, G. Cárdenas, J. Córdoba, M. J. Nadal, J. C. Nieto, S. Vidal, C. Villanueva, H. Bascuñana, C. Juárez, C. Guarner

Department of Medicine

Research output: Contribution to journal › Article › Research › peer-review

3 Citations (Scopus)

Abstract

Objetive: To evaluate the efficacy and safety of an exercise programme to increase muscle mass, effort tolerance and quality of life in cirrhotic patients. Patients and methods: Seventeen compensated cirrhotic patients were randomized into either an exercise group (n=8) or a control group (n=9). The programme of moderate exercise was given for 12 weeks. All patients received oral leucine (10 g/day) during the study. Anthropometric measurements, effort tolerance and quality of life were determined at study start and end. We also analysed the safety during the study. Results: In the exercise group thigh circumference increased (p=0.02) and effort tolerance improved (p=0.01) and 2-min step test (p=0.02). Moreover, quality of life improved significantly in this group. In the control group there were no statistically significant changes in any of the studied parameters. We did not observe complications of cirrhosis in either group. Conclusion: Our results suggest that moderate physical exercise in patients with compensated cirrhosis is safe and improves quality of life, effort tolerance and muscle mass.

Original language	English
Pages (from-to)	6-11
Journal	Trauma (Spain)
Volume	24
Issue number	1
Publication status	Published - 1 Jan 2013

Keywords

Cirrhosis
Exercise
Muscle mass
Quality of life

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@article{a78b19a435c442f0901d4338c3590956,

title = "Study of the benefit of an exercise programme and branched amino acid supplements in patients with liver cirrhosis",

abstract = "Objetive: To evaluate the efficacy and safety of an exercise programme to increase muscle mass, effort tolerance and quality of life in cirrhotic patients. Patients and methods: Seventeen compensated cirrhotic patients were randomized into either an exercise group (n=8) or a control group (n=9). The programme of moderate exercise was given for 12 weeks. All patients received oral leucine (10 g/day) during the study. Anthropometric measurements, effort tolerance and quality of life were determined at study start and end. We also analysed the safety during the study. Results: In the exercise group thigh circumference increased (p=0.02) and effort tolerance improved (p=0.01) and 2-min step test (p=0.02). Moreover, quality of life improved significantly in this group. In the control group there were no statistically significant changes in any of the studied parameters. We did not observe complications of cirrhosis in either group. Conclusion: Our results suggest that moderate physical exercise in patients with compensated cirrhosis is safe and improves quality of life, effort tolerance and muscle mass.",

keywords = "Cirrhosis, Exercise, Muscle mass, Quality of life",

author = "G. Soriano and E. Rom{\'a}n and Torrades, {M. T.} and G. C{\'a}rdenas and J. C{\'o}rdoba and Nadal, {M. J.} and Nieto, {J. C.} and S. Vidal and C. Villanueva and H. Bascu{\~n}ana and C. Ju{\'a}rez and C. Guarner",

year = "2013",

month = jan,

day = "1",

language = "English",

volume = "24",

pages = "6--11",

number = "1",

}

Study of the benefit of an exercise programme and branched amino acid supplements in patients with liver cirrhosis. / Soriano, G.; Román, E.; Torrades, M. T.; Cárdenas, G.; Córdoba, J.; Nadal, M. J.; Nieto, J. C.; Vidal, S.; Villanueva, C.; Bascuñana, H.; Juárez, C.; Guarner, C.

In: Trauma (Spain), Vol. 24, No. 1, 01.01.2013, p. 6-11.

Research output: Contribution to journal › Article › Research › peer-review

TY - JOUR

T1 - Study of the benefit of an exercise programme and branched amino acid supplements in patients with liver cirrhosis

AU - Soriano, G.

AU - Román, E.

AU - Torrades, M. T.

AU - Cárdenas, G.

AU - Córdoba, J.

AU - Nadal, M. J.

AU - Nieto, J. C.

AU - Vidal, S.

AU - Villanueva, C.

AU - Bascuñana, H.

AU - Juárez, C.

AU - Guarner, C.

PY - 2013/1/1

Y1 - 2013/1/1

N2 - Objetive: To evaluate the efficacy and safety of an exercise programme to increase muscle mass, effort tolerance and quality of life in cirrhotic patients. Patients and methods: Seventeen compensated cirrhotic patients were randomized into either an exercise group (n=8) or a control group (n=9). The programme of moderate exercise was given for 12 weeks. All patients received oral leucine (10 g/day) during the study. Anthropometric measurements, effort tolerance and quality of life were determined at study start and end. We also analysed the safety during the study. Results: In the exercise group thigh circumference increased (p=0.02) and effort tolerance improved (p=0.01) and 2-min step test (p=0.02). Moreover, quality of life improved significantly in this group. In the control group there were no statistically significant changes in any of the studied parameters. We did not observe complications of cirrhosis in either group. Conclusion: Our results suggest that moderate physical exercise in patients with compensated cirrhosis is safe and improves quality of life, effort tolerance and muscle mass.

AB - Objetive: To evaluate the efficacy and safety of an exercise programme to increase muscle mass, effort tolerance and quality of life in cirrhotic patients. Patients and methods: Seventeen compensated cirrhotic patients were randomized into either an exercise group (n=8) or a control group (n=9). The programme of moderate exercise was given for 12 weeks. All patients received oral leucine (10 g/day) during the study. Anthropometric measurements, effort tolerance and quality of life were determined at study start and end. We also analysed the safety during the study. Results: In the exercise group thigh circumference increased (p=0.02) and effort tolerance improved (p=0.01) and 2-min step test (p=0.02). Moreover, quality of life improved significantly in this group. In the control group there were no statistically significant changes in any of the studied parameters. We did not observe complications of cirrhosis in either group. Conclusion: Our results suggest that moderate physical exercise in patients with compensated cirrhosis is safe and improves quality of life, effort tolerance and muscle mass.

KW - Cirrhosis

KW - Exercise

KW - Muscle mass

KW - Quality of life

M3 - Article

VL - 24

SP - 6

EP - 11

IS - 1

ER -