Studies on structurally simple butenolides. VI. The polycyclic 3:1 adducts of protoanemonin with C-nucleophiles

Joaquim Bigorra, Josep Font, Rosa M. Ortuño, Francisco Sanchez-Ferrando, F. Florencio, S. Martinez-Carrera, S. Garcia-Blanco

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Abstract

X-Ray diffraction analysis yielded the constitution, configuration and conformation of a tetracyclic 3:1 adduct formed by reaction of protoanemonin 1 with lithium dimethylcuprate. The same configuration was assigned by analogy to other tetracyclic 3:1 adducts formed by reaction of 1 with lithium di-n-butylcuprate or di-methyl sodiomalonate. A pentacyclic 3:1 adduct also formed in the last reaction was fully assigned (constitution, configuration, conformation) by analysis of its 300 MHz 2-D COSY NMR spectrum. © 1985.
Original languageEnglish
Pages (from-to)5589-5594
JournalTetrahedron
Volume41
Issue number23
DOIs
Publication statusPublished - 1 Jan 1985

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