Studies conducted in Spain on concentrations in humans of persistent toxic compounds

Miquel Porta; Elisa Puigdomènech; Ferran Ballester; Javier Selva; Núria Ribas-Fitó; Luis Domínguez-Boada; Piedad Martín-Olmedo; Nicolás Olea; Sabrina Llop; Marieta Fernández

doi:10.1157/13123971

Studies conducted in Spain on concentrations in humans of persistent toxic compounds

Miquel Porta, Elisa Puigdomènech, Ferran Ballester, Javier Selva, Núria Ribas-Fitó, Luis Domínguez-Boada, Piedad Martín-Olmedo, Nicolás Olea, Sabrina Llop, Marieta Fernández

Department of Paediatrics, Obstetrics and Gynaecology and Preventive Medicine and Public Health

Research output: Contribution to journal › Review article › Research › peer-review

16 Citations (Scopus)

Abstract

No systematic review is available on studies conducted in Spain on human concentrations of persistent toxic substances (PTS). The objectives were: to identify studies conducted in Spain in the past 30 years that determined concentrations in humans of dichlorodiphenyltrichloroethane (DDT), dichlorodiphenyldichloroethane (DDE), hexachlorobenzene (HCB), hexachlorocyclohexane (HCH) and polychlorinated biphenyls (PCBs); and to summarize the main characteristics and results of each study. Studies are highly heterogeneous and most lack population representativeness. Concentrations of DDT and DDE might have decreased moderately in the last 20 years. Numerous fluctuations are apparent in levels of HCB, HCHs and PCBs, in some instances compatible with some stagnation. There are enormous differences in levels detected across and within studies: PTS concentrations of some individuals may be over 200-fold higher than those of others. The actual magnitude of human contamination by PTS and their trends across Spain - as well as the geographic and social heterogeneity - remain largely unknown.

Original language	English
Pages (from-to)	248-266
Journal	Gaceta Sanitaria
Volume	22
Issue number	3
DOIs	https://doi.org/10.1157/13123971
Publication status	Published - 1 May 2008

Keywords

Biomonitoring
Dichlorodiphenyldichloroethane
Dichlorodiphenyltrichloroethane
Hexachlorobenzene
Hexachlorocyclohexane
Lindane
Persistent organic pollutants
Persistent toxic substances
Spain
Stockholm Treaty

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title = "Studies conducted in Spain on concentrations in humans of persistent toxic compounds",

abstract = "No systematic review is available on studies conducted in Spain on human concentrations of persistent toxic substances (PTS). The objectives were: to identify studies conducted in Spain in the past 30 years that determined concentrations in humans of dichlorodiphenyltrichloroethane (DDT), dichlorodiphenyldichloroethane (DDE), hexachlorobenzene (HCB), hexachlorocyclohexane (HCH) and polychlorinated biphenyls (PCBs); and to summarize the main characteristics and results of each study. Studies are highly heterogeneous and most lack population representativeness. Concentrations of DDT and DDE might have decreased moderately in the last 20 years. Numerous fluctuations are apparent in levels of HCB, HCHs and PCBs, in some instances compatible with some stagnation. There are enormous differences in levels detected across and within studies: PTS concentrations of some individuals may be over 200-fold higher than those of others. The actual magnitude of human contamination by PTS and their trends across Spain - as well as the geographic and social heterogeneity - remain largely unknown.",

keywords = "Biomonitoring, Dichlorodiphenyldichloroethane, Dichlorodiphenyltrichloroethane, Hexachlorobenzene, Hexachlorocyclohexane, Lindane, Persistent organic pollutants, Persistent toxic substances, Spain, Stockholm Treaty",

author = "Miquel Porta and Elisa Puigdom{\`e}nech and Ferran Ballester and Javier Selva and N{\'u}ria Ribas-Fit{\'o} and Luis Dom{\'i}nguez-Boada and Piedad Mart{\'i}n-Olmedo and Nicol{\'a}s Olea and Sabrina Llop and Marieta Fern{\'a}ndez",

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AU - Porta, Miquel

AU - Puigdomènech, Elisa

AU - Ballester, Ferran

AU - Selva, Javier

AU - Ribas-Fitó, Núria

AU - Domínguez-Boada, Luis

AU - Martín-Olmedo, Piedad

AU - Olea, Nicolás

AU - Llop, Sabrina

AU - Fernández, Marieta

PY - 2008/5/1

Y1 - 2008/5/1

N2 - No systematic review is available on studies conducted in Spain on human concentrations of persistent toxic substances (PTS). The objectives were: to identify studies conducted in Spain in the past 30 years that determined concentrations in humans of dichlorodiphenyltrichloroethane (DDT), dichlorodiphenyldichloroethane (DDE), hexachlorobenzene (HCB), hexachlorocyclohexane (HCH) and polychlorinated biphenyls (PCBs); and to summarize the main characteristics and results of each study. Studies are highly heterogeneous and most lack population representativeness. Concentrations of DDT and DDE might have decreased moderately in the last 20 years. Numerous fluctuations are apparent in levels of HCB, HCHs and PCBs, in some instances compatible with some stagnation. There are enormous differences in levels detected across and within studies: PTS concentrations of some individuals may be over 200-fold higher than those of others. The actual magnitude of human contamination by PTS and their trends across Spain - as well as the geographic and social heterogeneity - remain largely unknown.

AB - No systematic review is available on studies conducted in Spain on human concentrations of persistent toxic substances (PTS). The objectives were: to identify studies conducted in Spain in the past 30 years that determined concentrations in humans of dichlorodiphenyltrichloroethane (DDT), dichlorodiphenyldichloroethane (DDE), hexachlorobenzene (HCB), hexachlorocyclohexane (HCH) and polychlorinated biphenyls (PCBs); and to summarize the main characteristics and results of each study. Studies are highly heterogeneous and most lack population representativeness. Concentrations of DDT and DDE might have decreased moderately in the last 20 years. Numerous fluctuations are apparent in levels of HCB, HCHs and PCBs, in some instances compatible with some stagnation. There are enormous differences in levels detected across and within studies: PTS concentrations of some individuals may be over 200-fold higher than those of others. The actual magnitude of human contamination by PTS and their trends across Spain - as well as the geographic and social heterogeneity - remain largely unknown.

KW - Biomonitoring

KW - Dichlorodiphenyldichloroethane

KW - Dichlorodiphenyltrichloroethane

KW - Hexachlorobenzene

KW - Hexachlorocyclohexane

KW - Lindane

KW - Persistent organic pollutants

KW - Persistent toxic substances

KW - Spain

KW - Stockholm Treaty

U2 - 10.1157/13123971

DO - 10.1157/13123971

M3 - Review article

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SP - 248

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JO - Gaceta Sanitaria

JF - Gaceta Sanitaria

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ER -

Studies conducted in Spain on concentrations in humans of persistent toxic compounds

Abstract

Keywords

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