Structural and Atropisomeric Factors Governing the Selectivity of Pyrimido-benzodiazipinones as Inhibitors of Kinases and Bromodomains

Jinhua Wang, Tatiana Erazo, Fleur M. Ferguson, Dennis L. Buckley, Nestor Gomez, Pau Muñoz-Guardiola, Nora Diéguez-Martínez, Xianming Deng, Mingfeng Hao, Walter Massefski, Oleg Fedorov, Nana Kwaku Offei-Addo, Paul M. Park, Lingling Dai, Amy Dibona, Kelly Becht, Nam Doo Kim, Michael R. McKeown, Justin M. Roberts, Jinwei ZhangTaebo Sim, Dario R. Alessi, James E. Bradner, Jose M. Lizcano, Stephen C. Blacklow, Jun Qi, Xiang Xu*, Nathanael S. Gray

*Corresponding author for this work

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19 Citations (Scopus)

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Chemical Compounds