TY - JOUR
T1 - Stromal tumours of the gastrointestinal tract: a clinicopathological and ploidy analysis of 33 cases
AU - Lerma, E.
AU - Oliva, E.
AU - Tugués, D.
AU - Prat, J.
PY - 1994/1/1
Y1 - 1994/1/1
N2 - The clinicopathological and DNA flow cytometric data of 33 patients with stromal tumours of the gastrointestinal tract (STGIT) were analysed to select pathological features of prognostic value. Tumours had been previously classified as benign (21 cases) or malignant (12 cases). Data relating to poor prognosis statistically were local invasion, pathological grade, size greater than 10 cm, mitotic index (MI) and necrosis. Pathological grade was related to local invasion. Aneuploidy did not correlate with poor survival although a common trend was detected between both. DNA content may help to predict prognosis of STGIT, but its real value has not yet been clearly established. Currently, stage (invasion), size, MI and pathological grade remain the most useful prognostic factors. © 1994 Springer-Verlag.
AB - The clinicopathological and DNA flow cytometric data of 33 patients with stromal tumours of the gastrointestinal tract (STGIT) were analysed to select pathological features of prognostic value. Tumours had been previously classified as benign (21 cases) or malignant (12 cases). Data relating to poor prognosis statistically were local invasion, pathological grade, size greater than 10 cm, mitotic index (MI) and necrosis. Pathological grade was related to local invasion. Aneuploidy did not correlate with poor survival although a common trend was detected between both. DNA content may help to predict prognosis of STGIT, but its real value has not yet been clearly established. Currently, stage (invasion), size, MI and pathological grade remain the most useful prognostic factors. © 1994 Springer-Verlag.
KW - Flow cytometry
KW - Gastrointestinal tract
KW - Ploidy
KW - Smooth muscle tumours
KW - Stromal tumours
U2 - https://doi.org/10.1007/BF00197388
DO - https://doi.org/10.1007/BF00197388
M3 - Article
VL - 424
SP - 19
EP - 24
JO - Virchows Archiv - A Pathological Anatomy and Histopathology
JF - Virchows Archiv - A Pathological Anatomy and Histopathology
SN - 0174-7398
ER -