TY - JOUR
T1 - Stereoselective synthesis of chiral precursors to cyclobutane carbocyclic nucleosides and oligopeptides
AU - Rouge, Pablo D.
AU - Moglioni, Albertina G.
AU - Moltrasio, Graciela Y.
AU - Ortuño, Rosa M.
PY - 2003/1/17
Y1 - 2003/1/17
N2 - Versatile and highly efficient synthetic routes leading to optically active cyclobutanones, γ-amino acids and δ-amino alcohols are described. These compounds are relevant synthetic precursors to enantiopure cyclobutane carbocyclic nucleosides and oligopeptides. (-)-(S)-Verbenone is the chiral starting material used and the key synthetic steps involve concerted rearrangements in acidic medium. © 2003 Elsevier Science Ltd. All rights reserved.
AB - Versatile and highly efficient synthetic routes leading to optically active cyclobutanones, γ-amino acids and δ-amino alcohols are described. These compounds are relevant synthetic precursors to enantiopure cyclobutane carbocyclic nucleosides and oligopeptides. (-)-(S)-Verbenone is the chiral starting material used and the key synthetic steps involve concerted rearrangements in acidic medium. © 2003 Elsevier Science Ltd. All rights reserved.
U2 - 10.1016/S0957-4166(02)00823-6
DO - 10.1016/S0957-4166(02)00823-6
M3 - Article
VL - 14
SP - 193
EP - 195
IS - 2
ER -