Stereoselective synthesis of chiral precursors to cyclobutane carbocyclic nucleosides and oligopeptides

Pablo D. Rouge; Albertina G. Moglioni; Graciela Y. Moltrasio; Rosa M. Ortuño

doi:10.1016/S0957-4166(02)00823-6

Stereoselective synthesis of chiral precursors to cyclobutane carbocyclic nucleosides and oligopeptides

Pablo D. Rouge, Albertina G. Moglioni, Graciela Y. Moltrasio, Rosa M. Ortuño

Department of Chemistry

Research output: Contribution to journal › Article › Research › peer-review

22 Citations (Scopus)

Abstract

Versatile and highly efficient synthetic routes leading to optically active cyclobutanones, γ-amino acids and δ-amino alcohols are described. These compounds are relevant synthetic precursors to enantiopure cyclobutane carbocyclic nucleosides and oligopeptides. (-)-(S)-Verbenone is the chiral starting material used and the key synthetic steps involve concerted rearrangements in acidic medium. © 2003 Elsevier Science Ltd. All rights reserved.

Original language	English
Pages (from-to)	193-195
Journal	Tetrahedron Asymmetry
Volume	14
Issue number	2
DOIs	https://doi.org/10.1016/S0957-4166(02)00823-6
Publication status	Published - 17 Jan 2003

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title = "Stereoselective synthesis of chiral precursors to cyclobutane carbocyclic nucleosides and oligopeptides",

abstract = "Versatile and highly efficient synthetic routes leading to optically active cyclobutanones, γ-amino acids and δ-amino alcohols are described. These compounds are relevant synthetic precursors to enantiopure cyclobutane carbocyclic nucleosides and oligopeptides. (-)-(S)-Verbenone is the chiral starting material used and the key synthetic steps involve concerted rearrangements in acidic medium. {\textcopyright} 2003 Elsevier Science Ltd. All rights reserved.",

author = "Rouge, {Pablo D.} and Moglioni, {Albertina G.} and Moltrasio, {Graciela Y.} and Ortu{\~n}o, {Rosa M.}",

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AU - Rouge, Pablo D.

AU - Moglioni, Albertina G.

AU - Moltrasio, Graciela Y.

AU - Ortuño, Rosa M.

PY - 2003/1/17

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N2 - Versatile and highly efficient synthetic routes leading to optically active cyclobutanones, γ-amino acids and δ-amino alcohols are described. These compounds are relevant synthetic precursors to enantiopure cyclobutane carbocyclic nucleosides and oligopeptides. (-)-(S)-Verbenone is the chiral starting material used and the key synthetic steps involve concerted rearrangements in acidic medium. © 2003 Elsevier Science Ltd. All rights reserved.

AB - Versatile and highly efficient synthetic routes leading to optically active cyclobutanones, γ-amino acids and δ-amino alcohols are described. These compounds are relevant synthetic precursors to enantiopure cyclobutane carbocyclic nucleosides and oligopeptides. (-)-(S)-Verbenone is the chiral starting material used and the key synthetic steps involve concerted rearrangements in acidic medium. © 2003 Elsevier Science Ltd. All rights reserved.

U2 - 10.1016/S0957-4166(02)00823-6

DO - 10.1016/S0957-4166(02)00823-6

M3 - Article

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