Stereoselective synthesis of (-)-(1R,2S)-2-aminocyclobutane-1-carboxylic acid, a conformationally constrained β-amino acid

Marta Martín-Vilà, Cristina Minguillón, Rosa M. Ortuño

Research output: Contribution to journalArticleResearchpeer-review

37 Citations (Scopus)

Abstract

The title compound as well as some derivatives have been synthesized for the first time in optically active form by means of a chemoenzymatic transformation used to induce asymmetry in achiral precursors. The enantio- and diastereomeric purity has been determined by HPLC and NMR techniques.
Original languageEnglish
Pages (from-to)4291-4294
JournalTetrahedron Asymmetry
Volume9
Issue number24
DOIs
Publication statusPublished - 24 Dec 1998

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