Stereochemical studies on the 1,3-dipolar cycloaddition of 3,4,5,6-tetrahydropyridine 1-oxide to 2(5H)-furanones

Pau Cid, Pedro de March, Marta Figueredo, Josep Font, Sergio Milán

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22 Citations (Scopus)

Abstract

The 1,3-dipolar cycloaddition of 3,4,5,6-tetrahydropyridine 1-oxide, 1, to 2(5H)-furanones 2, 3, and 4 is investigated. Crucial nmr data are indicated to determine the conformational equilibria and stereochemistry of the adducts. The major products arise from exo transition states. © 1992.
Original languageEnglish
Pages (from-to)667-670
JournalTetrahedron Letters
Volume33
Issue number5
DOIs
Publication statusPublished - 28 Jan 1992

Keywords

  • 1,3-dipolar cycloaddition
  • 2(5H)-furanones
  • 3,4,5,6-tetrahydropyridine 1-oxide
  • nmr
  • stereochemistry

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