Statistical models to study subtoxic concentrations for some standard mutagens in three colon cancer cell lines

Xavier Bardina, Laura Fernández, Elisabet Piñeiro, Jordi Surrallés, Antonia Velázquez

Research output: Contribution to journalArticleResearchpeer-review

Abstract

The aim of this work is to propose models to study the toxic effect of different concentrations of some standard mutagens in different colon cancer cell lines. We find estimates and, by means of an inverse regression problem, confidence intervals for the subtoxic concentration, that is the concentration that reduces by thirty percent the number of colonies obtained in the absence of mutagen.
Original languageEnglish
Pages (from-to)193-204
JournalSORT
Volume30
Issue number2
Publication statusPublished - 1 Jul 2006

Keywords

  • Confidence interval
  • Inverse regression problem
  • Subtoxic concentration

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