Statistical models to study subtoxic concentrations for some standard mutagens in three colon cancer cell lines

Xavier Bardina; Laura Fernández; Elisabet Piñeiro; Jordi Surrallés; Antonia Velázquez

Statistical models to study subtoxic concentrations for some standard mutagens in three colon cancer cell lines

Xavier Bardina, Laura Fernández, Elisabet Piñeiro, Jordi Surrallés, Antonia Velázquez

Research output: Contribution to journal › Article › Research › peer-review

Abstract

The aim of this work is to propose models to study the toxic effect of different concentrations of some standard mutagens in different colon cancer cell lines. We find estimates and, by means of an inverse regression problem, confidence intervals for the subtoxic concentration, that is the concentration that reduces by thirty percent the number of colonies obtained in the absence of mutagen.

Original language	English
Pages (from-to)	193-204
Journal	SORT
Volume	30
Issue number	2
Publication status	Published - 1 Jul 2006

Keywords

Confidence interval
Inverse regression problem
Subtoxic concentration

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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https://ddd.uab.cat/record/97481Licence: CC BY-NC-ND

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title = "Statistical models to study subtoxic concentrations for some standard mutagens in three colon cancer cell lines",

abstract = "The aim of this work is to propose models to study the toxic effect of different concentrations of some standard mutagens in different colon cancer cell lines. We find estimates and, by means of an inverse regression problem, confidence intervals for the subtoxic concentration, that is the concentration that reduces by thirty percent the number of colonies obtained in the absence of mutagen.",

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author = "Xavier Bardina and Laura Fern{\'a}ndez and Elisabet Pi{\~n}eiro and Jordi Surrall{\'e}s and Antonia Vel{\'a}zquez",

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T1 - Statistical models to study subtoxic concentrations for some standard mutagens in three colon cancer cell lines

AU - Bardina, Xavier

AU - Fernández, Laura

AU - Piñeiro, Elisabet

AU - Surrallés, Jordi

AU - Velázquez, Antonia

PY - 2006/7/1

Y1 - 2006/7/1

N2 - The aim of this work is to propose models to study the toxic effect of different concentrations of some standard mutagens in different colon cancer cell lines. We find estimates and, by means of an inverse regression problem, confidence intervals for the subtoxic concentration, that is the concentration that reduces by thirty percent the number of colonies obtained in the absence of mutagen.

AB - The aim of this work is to propose models to study the toxic effect of different concentrations of some standard mutagens in different colon cancer cell lines. We find estimates and, by means of an inverse regression problem, confidence intervals for the subtoxic concentration, that is the concentration that reduces by thirty percent the number of colonies obtained in the absence of mutagen.

KW - Confidence interval

KW - Inverse regression problem

KW - Subtoxic concentration

M3 - Article

SN - 1696-2281

VL - 30

SP - 193

EP - 204

JO - SORT

JF - SORT

IS - 2

ER -

Statistical models to study subtoxic concentrations for some standard mutagens in three colon cancer cell lines

Abstract

Keywords

UN SDGs

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