Spectrophotometric analysis of a pharmaceutical preparation by principal component regression

M. Blanco, J. Coello, F. González, H. Iturriaga, S. Maspoch

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33 Citations (Scopus)

Abstract

The use of a principal component regression procedure for quantitative analytical control of pharmaceutical preparations was investigated. The procedure was applied to the simultaneous quantitation of the active compound and preservative of a syrup by resolving their respective UV spectra. The most suitable conditions for quantitation were established and the results were compared with those obtained by HPLC. Copyright © 1993 Wiley‐Liss, Inc., A Wiley Company
Original languageEnglish
Pages (from-to)834-837
JournalJournal of Pharmaceutical Sciences
Volume82
Issue number8
DOIs
Publication statusPublished - 1 Jan 1993

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