Spectrophotometric analysis of a pharmaceutical preparation by principal component regression

M. Blanco; J. Coello; F. González; H. Iturriaga; S. Maspoch

doi:10.1002/jps.2600820816

Spectrophotometric analysis of a pharmaceutical preparation by principal component regression

M. Blanco, J. Coello, F. González, H. Iturriaga, S. Maspoch

Research output: Contribution to journal › Article › Research › peer-review

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Abstract

The use of a principal component regression procedure for quantitative analytical control of pharmaceutical preparations was investigated. The procedure was applied to the simultaneous quantitation of the active compound and preservative of a syrup by resolving their respective UV spectra. The most suitable conditions for quantitation were established and the results were compared with those obtained by HPLC. Copyright © 1993 Wiley‐Liss, Inc., A Wiley Company

Original language	English
Pages (from-to)	834-837
Journal	Journal of Pharmaceutical Sciences
Volume	82
Issue number	8
DOIs	https://doi.org/10.1002/jps.2600820816
Publication status	Published - 1 Jan 1993

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abstract = "The use of a principal component regression procedure for quantitative analytical control of pharmaceutical preparations was investigated. The procedure was applied to the simultaneous quantitation of the active compound and preservative of a syrup by resolving their respective UV spectra. The most suitable conditions for quantitation were established and the results were compared with those obtained by HPLC. Copyright {\textcopyright} 1993 Wiley‐Liss, Inc., A Wiley Company",

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