SPECT, coronary angio-CT, invasive coronary angiography and fusion images in stable coronary disease

M. N. Pizzi, S. Aguadé-Bruix, A. Roque, H. Cuéllar-Calabria, G. Romero-Farina, B. García del Blanco, J. Castell-Conesa, D. García-Dorado, J. Candell-Riera

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2 Citations (Scopus)


© 2014 Elsevier España, S.L.U. and SEMNIM. Objectives: To evaluate the usefulness of the information obtained with SPECT, coronary angio-CT and fusion images, in patients with stable ischemic disease who need invasive coronary angiography (IA). Material and methods: Forty-six patients (65.98 ± 8.3 years) with coronary disease were prospectively included. The fusion images generated after undergoing IA were used to evaluate the performance of these techniques in the diagnosis of multi-vessel coronary disease, the detection of the culprit vessel and the therapeutic management of these patients. Results: In the IA, 29 of the 46 patients (63%) had multi-vessel disease. SPECT could detect it in 48.2% and coronary angio-CT could detect it in 89.6%. Concordance between coronary angio-CT and IA in the diagnosis of the culprit vessel was 77% (kappa 0.6), and between SPECT and IA it was 73% (kappa 0.56). Although fusion images could have been obtained prior to IA, they would not have changed the therapeutic approach derived from SPECT and IA. Conclusions: Coronary angio-CT has a high ability for the diagnosis of multi-vessel disease and the culprit lesion, and SPECT is a good functional complement of the IA in the detection of the most ischemic territory. However, the performance of fusion images in patients with stable ischemic disease, who have undergone a SPECT as the first non-invasive study and need IA, does not seem indicated because they would not have changed the therapeutic management derived from SPECT and IA information.
Original languageEnglish
Pages (from-to)173-180
JournalRevista Espanola de Medicina Nuclear e Imagen Molecular
Issue number3
Publication statusPublished - 1 Jan 2015


  • Coronary angio-CT
  • Culprit vessel
  • Gated-SPECT
  • Multi-vessel disease
  • SPECT-CT image fusion
  • Stable ischemic disease


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