TY - JOUR
T1 - Smell–taste dysfunctions in extreme weight/eating conditions: analysis of hormonal and psychological interactions
AU - Fernández-Aranda, Fernando
AU - Agüera, Zaida
AU - Fernández-García, Jose C.
AU - Garrido-Sanchez, Lourdes
AU - Alcaide-Torres, Juan
AU - Tinahones, Francisco J.
AU - Giner-Bartolomé, Cristina
AU - Baños, Rosa M.
AU - Botella, Cristina
AU - Cebolla, Ausias
AU - de la Torre, Rafael
AU - Fernández-Real, Jose M.
AU - Ortega, Francisco J.
AU - Frühbeck, Gema
AU - Gómez-Ambrosi, Javier
AU - Granero, Roser
AU - Islam, Mohamed A.
AU - Jiménez-Murcia, Susana
AU - Tárrega, Salomé
AU - Menchón, José M.
AU - Fagundo, Ana B.
AU - Sancho, Carolina
AU - Estivill, Xavier
AU - Treasure, Janet
AU - Casanueva, Felipe F.
PY - 2016/2/1
Y1 - 2016/2/1
N2 - © 2015, Springer Science+Business Media New York. (1) The objective of this study is to analyze differences in smell–taste capacity between females in extreme weight/eating conditions (EWC) and (2) to explore the interaction between smell/taste capacity, gastric hormones, eating behavior and body mass index (BMI). The sample comprised 239 females in EWC [64 Anorexia nervosa (AN) and 80 age-matched healthy-weight controls, and 59 obese and 36 age-matched healthy-weight controls]. Smell and taste assessments were performed through “Sniffin’ Sticks” and “Taste Strips,” respectively. The assessment measures included the eating disorders inventory-2, the symptom check list 90-revised, and The Dutch Eating Behavior Questionnaire, as well as peptides from the gastrointestinal tract [Ghrelin, peptide YY, cholecystokinin]. Smell capacity was differentially associated across EWC groups. Smell was clearly impaired in obese participants and increased in AN (hyposmia in Obesity was 54.3 and 6.4 % in AN), but taste capacity did not vary across EWC. Ghrelin levels were significantly decreased in obese subjects and were related to smell impairment. EWC individuals showed a distinct smell profile and circulating ghrelin levels compared to controls. Smell capacity and ghrelin may act as moderators of emotional eating and BMI.
AB - © 2015, Springer Science+Business Media New York. (1) The objective of this study is to analyze differences in smell–taste capacity between females in extreme weight/eating conditions (EWC) and (2) to explore the interaction between smell/taste capacity, gastric hormones, eating behavior and body mass index (BMI). The sample comprised 239 females in EWC [64 Anorexia nervosa (AN) and 80 age-matched healthy-weight controls, and 59 obese and 36 age-matched healthy-weight controls]. Smell and taste assessments were performed through “Sniffin’ Sticks” and “Taste Strips,” respectively. The assessment measures included the eating disorders inventory-2, the symptom check list 90-revised, and The Dutch Eating Behavior Questionnaire, as well as peptides from the gastrointestinal tract [Ghrelin, peptide YY, cholecystokinin]. Smell capacity was differentially associated across EWC groups. Smell was clearly impaired in obese participants and increased in AN (hyposmia in Obesity was 54.3 and 6.4 % in AN), but taste capacity did not vary across EWC. Ghrelin levels were significantly decreased in obese subjects and were related to smell impairment. EWC individuals showed a distinct smell profile and circulating ghrelin levels compared to controls. Smell capacity and ghrelin may act as moderators of emotional eating and BMI.
KW - Anorexia nervosa
KW - Emotional eating
KW - Ghrelin
KW - Obesity
KW - Smell
KW - Taste
U2 - 10.1007/s12020-015-0684-9
DO - 10.1007/s12020-015-0684-9
M3 - Article
VL - 51
SP - 256
EP - 267
IS - 2
ER -
