Skin lesions in canine leishmaniasis

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    Forty‐three dogs affected by canine leishmaniasis (CL) with skin lesions have been studied clinically and histopathologically. Identification of leishmaniads in tissues was achieved using indirect immunoperoxidase staining. According to both macroscopic and microscopic lesions, four different dermatological patterns have been observed. Twenty‐six dogs showed alopecia and desquamation as the main skin lesions. Histologically a diffuse non‐suppurative dermatitis, with numerous leishmaniads inside macrophages was present. Ten animals showed skin ulcerations on limbs, especially over articulations. Histologically, the number of leishmaniads was very reduced. Five animals presented a generalised nodular disease. Each nodule corresponded with a focal accumulation of macrophages, multinucleated giant cells and lymphocytes, with a high number of parasites. Finally, two dogs presented generalised skin pustules. The possible pathogenesis and the differential diagnosis of each form is discussed. Copyright © 1988, Wiley Blackwell. All rights reserved
    Original languageEnglish
    Pages (from-to)381-388
    JournalJournal of Small Animal Practice
    Issue number6
    Publication statusPublished - 1 Jan 1988


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