Skin eruption in primary human immunodeficiency virus infection

Albert Xifra; Isabel Bielsa; Miquel Ribera; Natalia Fernández-Chico; Xavier Soria; Carlos Ferrándiz

Skin eruption in primary human immunodeficiency virus infection

Albert Xifra, Isabel Bielsa, Miquel Ribera, Natalia Fernández-Chico, Xavier Soria, Carlos Ferrándiz

Department of Medicine

Research output: Contribution to journal › Article › Research › peer-review

1 Citation (Scopus)

Abstract

Although primary HIV infection is symptomatic in 50-90% of cases, it may go unnoticed in most of them. The clinical manifestations as a whole are known as acute retroviral syndrome, which is related to the high rate of replication of the retrovirus and the immune system's strong response to it. The most frequent symptoms are fever, fatigue, skin eruption and generalized lymphadenopathies, which usually appear between the 2nd and 4th weeks of the infection. The eruption usually involves the face and upper third of the trunk, and shows orangish-erythematous macules and papules, rounded and non-confluent, some with central necrosis. On many occasions, it is accompanied by involvement of the mucous membranes. We describe four cases of primary HIV infection. The diagnosis in this stage of the disease is established by means of non-serological laboratory techniques (viral load, proviral DNA) and makes it possible to initiate early antiretroviral treatment.

Original language	English
Pages (from-to)	385-389
Journal	Actas Dermo-Sifiliograficas
Volume	95
Issue number	6
Publication status	Published - 1 Jan 2004

Keywords

Diagnosis
Primary HIV infection
Skin eruption

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title = "Skin eruption in primary human immunodeficiency virus infection",

abstract = "Although primary HIV infection is symptomatic in 50-90% of cases, it may go unnoticed in most of them. The clinical manifestations as a whole are known as acute retroviral syndrome, which is related to the high rate of replication of the retrovirus and the immune system's strong response to it. The most frequent symptoms are fever, fatigue, skin eruption and generalized lymphadenopathies, which usually appear between the 2nd and 4th weeks of the infection. The eruption usually involves the face and upper third of the trunk, and shows orangish-erythematous macules and papules, rounded and non-confluent, some with central necrosis. On many occasions, it is accompanied by involvement of the mucous membranes. We describe four cases of primary HIV infection. The diagnosis in this stage of the disease is established by means of non-serological laboratory techniques (viral load, proviral DNA) and makes it possible to initiate early antiretroviral treatment.",

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T1 - Skin eruption in primary human immunodeficiency virus infection

AU - Xifra, Albert

AU - Bielsa, Isabel

AU - Ribera, Miquel

AU - Fernández-Chico, Natalia

AU - Soria, Xavier

AU - Ferrándiz, Carlos

PY - 2004/1/1

Y1 - 2004/1/1

N2 - Although primary HIV infection is symptomatic in 50-90% of cases, it may go unnoticed in most of them. The clinical manifestations as a whole are known as acute retroviral syndrome, which is related to the high rate of replication of the retrovirus and the immune system's strong response to it. The most frequent symptoms are fever, fatigue, skin eruption and generalized lymphadenopathies, which usually appear between the 2nd and 4th weeks of the infection. The eruption usually involves the face and upper third of the trunk, and shows orangish-erythematous macules and papules, rounded and non-confluent, some with central necrosis. On many occasions, it is accompanied by involvement of the mucous membranes. We describe four cases of primary HIV infection. The diagnosis in this stage of the disease is established by means of non-serological laboratory techniques (viral load, proviral DNA) and makes it possible to initiate early antiretroviral treatment.

AB - Although primary HIV infection is symptomatic in 50-90% of cases, it may go unnoticed in most of them. The clinical manifestations as a whole are known as acute retroviral syndrome, which is related to the high rate of replication of the retrovirus and the immune system's strong response to it. The most frequent symptoms are fever, fatigue, skin eruption and generalized lymphadenopathies, which usually appear between the 2nd and 4th weeks of the infection. The eruption usually involves the face and upper third of the trunk, and shows orangish-erythematous macules and papules, rounded and non-confluent, some with central necrosis. On many occasions, it is accompanied by involvement of the mucous membranes. We describe four cases of primary HIV infection. The diagnosis in this stage of the disease is established by means of non-serological laboratory techniques (viral load, proviral DNA) and makes it possible to initiate early antiretroviral treatment.

KW - Diagnosis

KW - Primary HIV infection

KW - Skin eruption

M3 - Article

VL - 95

SP - 385

EP - 389

IS - 6

ER -