Sister-chromatid exchanges (SCE) induced by p-dichlorobenzene in cultured human lymphocytes

E. Carbonell; M. Puig; N. Xamena; A. Creus; R. Marcos

doi:10.1016/0165-7992(91)90035-3

Sister-chromatid exchanges (SCE) induced by p-dichlorobenzene in cultured human lymphocytes

E. Carbonell, M. Puig, N. Xamena, A. Creus, R. Marcos

Department of Genetics and Microbiology

Research output: Contribution to journal › Article › Research › peer-review

8 Citations (Scopus)

Abstract

We have investigated the ability of p-dichlorobenzene (p-DCB) to induce sister-chromatid exchanges (SCE) in cultured human lymphocytes. From our results we can conclude that p-DCB was able to induce a cytotoxic effect, measured as a decrease in third and second metaphases, together with an increase of SCEs. © 1991.

Original language	English
Pages (from-to)	57-59
Journal	Mutation Research Letters
Volume	263
Issue number	1
DOIs	https://doi.org/10.1016/0165-7992(91)90035-3
Publication status	Published - 1 Jan 1991

Keywords

Human lymphocytes
p-Dichlorobenzene
Sister-chromatid exchanges

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abstract = "We have investigated the ability of p-dichlorobenzene (p-DCB) to induce sister-chromatid exchanges (SCE) in cultured human lymphocytes. From our results we can conclude that p-DCB was able to induce a cytotoxic effect, measured as a decrease in third and second metaphases, together with an increase of SCEs. {\textcopyright} 1991.",

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AU - Carbonell, E.

AU - Puig, M.

AU - Xamena, N.

AU - Creus, A.

AU - Marcos, R.

PY - 1991/1/1

Y1 - 1991/1/1

N2 - We have investigated the ability of p-dichlorobenzene (p-DCB) to induce sister-chromatid exchanges (SCE) in cultured human lymphocytes. From our results we can conclude that p-DCB was able to induce a cytotoxic effect, measured as a decrease in third and second metaphases, together with an increase of SCEs. © 1991.

AB - We have investigated the ability of p-dichlorobenzene (p-DCB) to induce sister-chromatid exchanges (SCE) in cultured human lymphocytes. From our results we can conclude that p-DCB was able to induce a cytotoxic effect, measured as a decrease in third and second metaphases, together with an increase of SCEs. © 1991.

KW - Human lymphocytes

KW - p-Dichlorobenzene

KW - Sister-chromatid exchanges

U2 - 10.1016/0165-7992(91)90035-3

DO - 10.1016/0165-7992(91)90035-3

M3 - Article

VL - 263

SP - 57

EP - 59

JO - Mutation Research Letters

JF - Mutation Research Letters

SN - 0165-7992

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