TY - JOUR
T1 - Single Center Experience Combining Multiple Tools for Genetic Diagnosis of B-Cell Acute Lymphoblastic Leukemia
AU - Hidalgo‐Gómez, Gloria
AU - Tazón-Vega, Bárbara
AU - Palacio-Garcia, Carlos
AU - Saumell, Silvia
AU - Gabarrós-Subirà, María
AU - Jerez, Andrés
AU - Blanco, Adoración
AU - Martínez-Morgado, Noemí
AU - Navarro Garces, Víctor
AU - Murillo, Laura
AU - Velasco Puyo, Pablo
AU - Murciano Carrillo, Thaïs
AU - Diaz-Heredia, Cristina
AU - Bosch Albareda, Francesc
AU - Armengol, Gemma
AU - Ortega Blanco, Margarita
PY - 2024/11/5
Y1 - 2024/11/5
N2 - Pediatric B-cell acute lymphoblastic leukemia (B-ALL) is characterized by distinct genetic pro les essential for prognosis and treatment. About 70% of B-ALL cases can be classi ed into well-known genetic subtypes, while 30% remain under the "B-other" category. Accurate genetic diagnosis requires multiple techniques; however, their accessibility varies signi cantly among laboratories. This study investigates an integrated approach to classify B-ALL into genetic subtypes, elucidate their frequency and clinical signi cance, and identify the most effective diagnostic methods.
AB - Pediatric B-cell acute lymphoblastic leukemia (B-ALL) is characterized by distinct genetic pro les essential for prognosis and treatment. About 70% of B-ALL cases can be classi ed into well-known genetic subtypes, while 30% remain under the "B-other" category. Accurate genetic diagnosis requires multiple techniques; however, their accessibility varies signi cantly among laboratories. This study investigates an integrated approach to classify B-ALL into genetic subtypes, elucidate their frequency and clinical signi cance, and identify the most effective diagnostic methods.
U2 - 10.1182/blood-2024-209957
DO - 10.1182/blood-2024-209957
M3 - Article
SN - 0006-4971
VL - 144
SP - 2803
EP - 2804
JO - Blood
JF - Blood
IS - Supplement 1
ER -