Simultaneous presence of C-ANCA and P-ANCA in a patient with concurrent Churg-Strauss syndrome and giant cell temporal arteritis

Josep M. Guardiola, A. Rodríguez-Pla, J. López-Contreras, J. M. Llobet, P. Domingo, M. Franco, C. Díaz, G. Vázquez

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9 Citations (Scopus)

Abstract

We herein describe the case of a 77-year-old woman, who presented clinical and histopathological evidence of giant cell arteritis (GCA) involving the temporal artery, together with a Churg-Strauss syndrome (CSS). Our patient presented positive anti-neutrophil cytoplasmic antibodies (ANCA), with cytoplasmic staining pattern (C-ANCA) that was specific against proteinase 3 (PR3), and also a perinuclear pattern (P-ANCA) with specificity against myeloperoxidase (MPO). To our knowledge, the simultaneous presence in the same patient of both types of antibodies has not been previously reported.
Original languageEnglish
Pages (from-to)68-69
JournalScandinavian Journal of Rheumatology
Volume29
Issue number1
Publication statusPublished - 26 Feb 2000

Keywords

  • Anti-neutrophil antibodies
  • Churg-Strauss
  • Giant cell arteritis
  • Myeloperoxidase
  • Proteinase 3

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