Sex and restraint stress differences in rat metallothionein and Zn levels.

Juan Hidalgo; M. Giralt; J. S. Garvey; A. Armario

Sex and restraint stress differences in rat metallothionein and Zn levels.

Juan Hidalgo^*, M. Giralt, J. S. Garvey, A. Armario

^*Corresponding author for this work

Research output: Contribution to journal › Article › Research › peer-review

4 Citations (Scopus)

Abstract

Sex differences in serum and liver metallothionein (MT) levels were studied in adult male and female rats. Whereas it was found that female rats had higher hepatic MT levels than male rats in basal, unstressed conditions, no significant differences were found in serum MT levels. Restraint stress increased both serum and liver MT in both sexes. The increase in serum MT was greater in male than in female rats, whereas no significant differences between sexes were found in liver MT content after restraint stress. It is suggested that MT regulation might be sex-dependent and that MT might play some extrahepatic function during stress.

Original language	Spanish
Pages (from-to)	427-431
Journal	Revista Espanola de Fisiologia
Volume	43
Issue number	4
Publication status	Published - 1 Jan 1987

Cite this

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title = "Sex and restraint stress differences in rat metallothionein and Zn levels.",

abstract = "Sex differences in serum and liver metallothionein (MT) levels were studied in adult male and female rats. Whereas it was found that female rats had higher hepatic MT levels than male rats in basal, unstressed conditions, no significant differences were found in serum MT levels. Restraint stress increased both serum and liver MT in both sexes. The increase in serum MT was greater in male than in female rats, whereas no significant differences between sexes were found in liver MT content after restraint stress. It is suggested that MT regulation might be sex-dependent and that MT might play some extrahepatic function during stress.",

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year = "1987",

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T1 - Sex and restraint stress differences in rat metallothionein and Zn levels.

AU - Hidalgo, Juan

AU - Giralt, M.

AU - Garvey, J. S.

AU - Armario, A.

PY - 1987/1/1

Y1 - 1987/1/1

N2 - Sex differences in serum and liver metallothionein (MT) levels were studied in adult male and female rats. Whereas it was found that female rats had higher hepatic MT levels than male rats in basal, unstressed conditions, no significant differences were found in serum MT levels. Restraint stress increased both serum and liver MT in both sexes. The increase in serum MT was greater in male than in female rats, whereas no significant differences between sexes were found in liver MT content after restraint stress. It is suggested that MT regulation might be sex-dependent and that MT might play some extrahepatic function during stress.

AB - Sex differences in serum and liver metallothionein (MT) levels were studied in adult male and female rats. Whereas it was found that female rats had higher hepatic MT levels than male rats in basal, unstressed conditions, no significant differences were found in serum MT levels. Restraint stress increased both serum and liver MT in both sexes. The increase in serum MT was greater in male than in female rats, whereas no significant differences between sexes were found in liver MT content after restraint stress. It is suggested that MT regulation might be sex-dependent and that MT might play some extrahepatic function during stress.

M3 - Artículo

SN - 0034-9402

VL - 43

SP - 427

EP - 431

JO - Revista Espanola de Fisiologia

JF - Revista Espanola de Fisiologia

IS - 4

ER -