Severe hypertriglyceridemia associated with teriflunomide in a patient with multiple sclerosis: A case report

Carlos R. Camara-Lemarroy; Joaquín Castilló; Jaume Sastre-Garriga; Mar Tintore; Xavier Montalban

doi:10.1177/1352458518761185

Severe hypertriglyceridemia associated with teriflunomide in a patient with multiple sclerosis: A case report

Carlos R. Camara-Lemarroy, Joaquín Castilló, Jaume Sastre-Garriga, Mar Tintore, Xavier Montalban

Department of Medicine

Research output: Contribution to journal › Article › Research › peer-review

5 Citations (Scopus)

Abstract

© The Author(s), 2018. Objective: To describe a case of severe hypertriglyceridemia in a patient receiving teriflunomide. Methods: This is a case study. Results: Our patient developed severe hypertriglyceridemia (>5000 mg/dL) while on teriflunomide. The drug was withdrawn. Resolution began over 3 weeks later. Conclusion: We describe the first probable case of teriflunomide-associated severe hypertriglyceridemia in a patient with multiple sclerosis, an adverse event previously associated with leflunomide in patients with rheumatologic diseases. Clinicians should be aware of this rare but potentially dangerous adverse event.

Original language	English
Pages (from-to)	1383-1385
Journal	Multiple Sclerosis Journal
Volume	24
Issue number	10
DOIs	https://doi.org/10.1177/1352458518761185
Publication status	Published - 1 Sept 2018

Keywords

Teriflunomide
hypertriglyceridemia
multiple sclerosis

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10.1177/1352458518761185

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title = "Severe hypertriglyceridemia associated with teriflunomide in a patient with multiple sclerosis: A case report",

abstract = "{\textcopyright} The Author(s), 2018. Objective: To describe a case of severe hypertriglyceridemia in a patient receiving teriflunomide. Methods: This is a case study. Results: Our patient developed severe hypertriglyceridemia (>5000 mg/dL) while on teriflunomide. The drug was withdrawn. Resolution began over 3 weeks later. Conclusion: We describe the first probable case of teriflunomide-associated severe hypertriglyceridemia in a patient with multiple sclerosis, an adverse event previously associated with leflunomide in patients with rheumatologic diseases. Clinicians should be aware of this rare but potentially dangerous adverse event.",

keywords = "Teriflunomide, hypertriglyceridemia, multiple sclerosis",

author = "Camara-Lemarroy, {Carlos R.} and Joaqu{\'i}n Castill{\'o} and Jaume Sastre-Garriga and Mar Tintore and Xavier Montalban",

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AU - Camara-Lemarroy, Carlos R.

AU - Castilló, Joaquín

AU - Sastre-Garriga, Jaume

AU - Tintore, Mar

AU - Montalban, Xavier

PY - 2018/9/1

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N2 - © The Author(s), 2018. Objective: To describe a case of severe hypertriglyceridemia in a patient receiving teriflunomide. Methods: This is a case study. Results: Our patient developed severe hypertriglyceridemia (>5000 mg/dL) while on teriflunomide. The drug was withdrawn. Resolution began over 3 weeks later. Conclusion: We describe the first probable case of teriflunomide-associated severe hypertriglyceridemia in a patient with multiple sclerosis, an adverse event previously associated with leflunomide in patients with rheumatologic diseases. Clinicians should be aware of this rare but potentially dangerous adverse event.

AB - © The Author(s), 2018. Objective: To describe a case of severe hypertriglyceridemia in a patient receiving teriflunomide. Methods: This is a case study. Results: Our patient developed severe hypertriglyceridemia (>5000 mg/dL) while on teriflunomide. The drug was withdrawn. Resolution began over 3 weeks later. Conclusion: We describe the first probable case of teriflunomide-associated severe hypertriglyceridemia in a patient with multiple sclerosis, an adverse event previously associated with leflunomide in patients with rheumatologic diseases. Clinicians should be aware of this rare but potentially dangerous adverse event.

KW - Teriflunomide

KW - hypertriglyceridemia

KW - multiple sclerosis

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JO - Multiple Sclerosis Journal

JF - Multiple Sclerosis Journal

IS - 10

ER -

Severe hypertriglyceridemia associated with teriflunomide in a patient with multiple sclerosis: A case report

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Keywords

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