Serum chemistry reference values for the common genet (Genetta genetta): variations associated with Leishmania infantum infection

Javier Millán, Andrea D. Chirife, Laura Altet

    Research output: Contribution to journalArticleResearchpeer-review

    5 Citations (Scopus)

    Abstract

    © 2015, © 2014 Taylor & Francis. Background: The role of wildlife in the epidemiology of leishmaniosis in under debate, and determining whether infection with Leishmania infantum causes illness in wild carnivores is important to determine its potential role as a reservoir. Objectives: To provide for the first time serum biochemistry reference values for the common genet (Genetta genetta), and to determine variations associated with L. infantum infection. Methods: Twenty-five serum biochemistry parameters were determined in 22 wild-caught genets. Blood samples were analyzed for L. infantum DNA by means of real-time polymerase chain reaction (PCR). Results: Two female genets were positive for L. infantum DNA but did not show any external clinical sign upon physical examination. Among other variations in the biochemistry values of these genets, one presented a higher concentration of gamma-globulins and cholesterol, whereas the other genet presented increased creatinine, bilirubin, and chloride levels when compared to uninfected females. Sex-related differences in some parameters were also reported. Conclusion: Infection with L. infantum may sometimes be accompanied by abnormal serum biochemistry in wild carnivores. Clinical importance: Clinical disease may occur in L. infantum-infected wild carnivores. This has implications in the epidemiology of leishmaniosis. In addition, the data provided here would also be useful as reference values for researchers or rehabilitators working with the common genet.
    Original languageEnglish
    Pages (from-to)43-47
    JournalVeterinary Quarterly
    Volume35
    Issue number1
    DOIs
    Publication statusPublished - 2 Jan 2015

    Keywords

    • biochemistry
    • common genet
    • Genetta genetta
    • Leishmania infantum
    • leishmaniosis

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