Serum acute phase proteins in Dirofilaria immitis and Wolbachia seropositive cats

Ana C. Silvestre-Ferreira; Lisete Vieira; Hugo Vilhena; Jose J. Cerón; Asta Tvarijonaviciute; José A. Montoya-Alonso; Elena Carretón; Josep Pastor

doi:10.1177/1098612X15625435

Serum acute phase proteins in Dirofilaria immitis and Wolbachia seropositive cats

Ana C. Silvestre-Ferreira, Lisete Vieira, Hugo Vilhena, Jose J. Cerón, Asta Tvarijonaviciute, José A. Montoya-Alonso, Elena Carretón, Josep Pastor

Research output: Contribution to journal › Article › Research › peer-review

6 Citations (Scopus)

Abstract

© 2016, © The Author(s) 2016. Objectives: The aim of this study was to characterise the response of acute phase proteins (APPs) in cats seropositive for Dirofilaria immitis and to its endosymbiont bacterium Wolbachia. Methods: The APPs serum amyloid A (SAA), haptoglobin (Hp) and ceruloplasmin (Cp) were measured in 25 seropositive cats and in 16 healthy seronegative cats. Results: SAA and Cp concentrations were significantly higher in animals with D immitis seropositivity that exhibited clinical signs related to the disease, and Hp was elevated in all D immitis-seropositive animals. There was no significant correlation between APPs and D immitis or Wolbachia species antibody titres. Conclusions and relevance: An association between feline seropositivity to D immitis and APP response was demonstrated. Increases in serum SAA and Cp concentrations were related to D immitis-associated clinical signs, whereas Hp increased in all seropositive animals.

Original language	English
Pages (from-to)	693-696
Journal	Journal of Feline Medicine and Surgery
Volume	19
Issue number	6
DOIs	https://doi.org/10.1177/1098612X15625435
Publication status	Published - 1 Jun 2017

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@article{4f38f2fbaea940aca5c3690df62d3e75,

title = "Serum acute phase proteins in Dirofilaria immitis and Wolbachia seropositive cats",

abstract = "{\textcopyright} 2016, {\textcopyright} The Author(s) 2016. Objectives: The aim of this study was to characterise the response of acute phase proteins (APPs) in cats seropositive for Dirofilaria immitis and to its endosymbiont bacterium Wolbachia. Methods: The APPs serum amyloid A (SAA), haptoglobin (Hp) and ceruloplasmin (Cp) were measured in 25 seropositive cats and in 16 healthy seronegative cats. Results: SAA and Cp concentrations were significantly higher in animals with D immitis seropositivity that exhibited clinical signs related to the disease, and Hp was elevated in all D immitis-seropositive animals. There was no significant correlation between APPs and D immitis or Wolbachia species antibody titres. Conclusions and relevance: An association between feline seropositivity to D immitis and APP response was demonstrated. Increases in serum SAA and Cp concentrations were related to D immitis-associated clinical signs, whereas Hp increased in all seropositive animals.",

author = "Silvestre-Ferreira, {Ana C.} and Lisete Vieira and Hugo Vilhena and Cer{\'o}n, {Jose J.} and Asta Tvarijonaviciute and Montoya-Alonso, {Jos{\'e} A.} and Elena Carret{\'o}n and Josep Pastor",

year = "2017",

month = jun,

day = "1",

doi = "10.1177/1098612X15625435",

language = "English",

volume = "19",

pages = "693--696",

journal = "Journal of Feline Medicine and Surgery",

issn = "1098-612X",

publisher = "W.B. Saunders Ltd",

number = "6",

}

Serum acute phase proteins in Dirofilaria immitis and Wolbachia seropositive cats. / Silvestre-Ferreira, Ana C.; Vieira, Lisete; Vilhena, Hugo; Cerón, Jose J.; Tvarijonaviciute, Asta; Montoya-Alonso, José A.; Carretón, Elena; Pastor, Josep.

In: Journal of Feline Medicine and Surgery, Vol. 19, No. 6, 01.06.2017, p. 693-696.

Research output: Contribution to journal › Article › Research › peer-review

TY - JOUR

T1 - Serum acute phase proteins in Dirofilaria immitis and Wolbachia seropositive cats

AU - Silvestre-Ferreira, Ana C.

AU - Vieira, Lisete

AU - Vilhena, Hugo

AU - Cerón, Jose J.

AU - Tvarijonaviciute, Asta

AU - Montoya-Alonso, José A.

AU - Carretón, Elena

AU - Pastor, Josep

PY - 2017/6/1

Y1 - 2017/6/1

N2 - © 2016, © The Author(s) 2016. Objectives: The aim of this study was to characterise the response of acute phase proteins (APPs) in cats seropositive for Dirofilaria immitis and to its endosymbiont bacterium Wolbachia. Methods: The APPs serum amyloid A (SAA), haptoglobin (Hp) and ceruloplasmin (Cp) were measured in 25 seropositive cats and in 16 healthy seronegative cats. Results: SAA and Cp concentrations were significantly higher in animals with D immitis seropositivity that exhibited clinical signs related to the disease, and Hp was elevated in all D immitis-seropositive animals. There was no significant correlation between APPs and D immitis or Wolbachia species antibody titres. Conclusions and relevance: An association between feline seropositivity to D immitis and APP response was demonstrated. Increases in serum SAA and Cp concentrations were related to D immitis-associated clinical signs, whereas Hp increased in all seropositive animals.

AB - © 2016, © The Author(s) 2016. Objectives: The aim of this study was to characterise the response of acute phase proteins (APPs) in cats seropositive for Dirofilaria immitis and to its endosymbiont bacterium Wolbachia. Methods: The APPs serum amyloid A (SAA), haptoglobin (Hp) and ceruloplasmin (Cp) were measured in 25 seropositive cats and in 16 healthy seronegative cats. Results: SAA and Cp concentrations were significantly higher in animals with D immitis seropositivity that exhibited clinical signs related to the disease, and Hp was elevated in all D immitis-seropositive animals. There was no significant correlation between APPs and D immitis or Wolbachia species antibody titres. Conclusions and relevance: An association between feline seropositivity to D immitis and APP response was demonstrated. Increases in serum SAA and Cp concentrations were related to D immitis-associated clinical signs, whereas Hp increased in all seropositive animals.

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DO - 10.1177/1098612X15625435

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