Sarcoptes scabiei: Specific immune response to sarcoptic mange in the Iberian ibex Capra pyrenaica depends on previous exposure and sex

Mathieu Sarasa, Luisa Rambozzi, Luca Rossi, Pier G. Meneguz, Emmanuel Serrano, José Enrique Granados, Francisco J. González, Paulino Fandos, Ramón C. Soriguer, Georges Gonzalez, Jean Joachim, Jesús M. Pérez

Research output: Contribution to journalArticleResearchpeer-review

43 Citations (Scopus)

Abstract

Host acquired immunity is a critical factor that conditions the survival of parasites. Nevertheless, there is a shortage of data concerning inter-individual immunological inequalities in wild mammals. Sarcoptic mange is a widespread parasitosis that severely affects mammals such as the Iberian ibex (Capra pyrenaica). Despite some work on the subject, the immune response to sarcoptic mange infestation is still a complex and poorly understood phenomenon. To improve knowledge of the host-. Sarcoptes immunological interaction, 18 Iberian ibexes were experimentally infested. IgG levels were assessed using ELISA to test for potential factors determining the specific immune response to infestation. Previous exposure and sex appeared to affect the IgG response to infestation and our results suggest a sex-biased immunomodulation. We discuss the immunological pattern of host-. Sarcoptes interactions and also suggest further lines of work that may improve the understanding of immunological interactions of host-Sarcoptes systems. © 2009 Elsevier Inc.
Original languageEnglish
Pages (from-to)265-271
JournalExperimental Parasitology
Volume124
Issue number3
DOIs
Publication statusPublished - 1 Mar 2010

Keywords

  • Capra pyrenaica
  • Immunity
  • Inter-individual variability
  • Sarcoptes scabiei
  • Ungulate

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