Abstract
© 2017 American Society for Microbiology. All Rights Reserved. Infections caused by multidrug-resistant Pseudomonas aeruginosa (MDRPA) present a major problem for therapeutic management. We report here our experience with 12 patients with a severe MDRPA infection (6 of which were pneumonia) who received salvage therapy with ceftolozane-tazobactam after inappropriate empirical treatment and/or suboptimal targeted treatment. Although 10 of the 12 patients (83.3%) experienced septic shock, only 3 patients (25%) died during the follow-up period. Microbiological cure in 7 patients (58.3%) was observed.
Original language | English |
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Article number | e02136 |
Journal | Antimicrobial Agents and Chemotherapy |
Volume | 61 |
Issue number | 3 |
DOIs | |
Publication status | Published - 1 Mar 2017 |
Keywords
- Ceftolozane-tazobactam
- Pseudomonas aeruginosa
- Salvage therapy