Abstract
The Salmonella enterica serovar Typhimurium znuABC genes encoding a high-affinity zinc uptake system and its regulatory zur gene have been cloned. Salmonella serovar Typhimurium zur and znuC knockout mutants have been constructed by marker exchange. The 50% lethal dose of the znuC mutant increased when either orally or intraperitoneally inoculated in BALB/c mice, while virulence of the zur mutant decreased only when mice were intraperitoneally challenged.
Original language | English |
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Pages (from-to) | 4721-4725 |
Journal | Infection and Immunity |
Volume | 70 |
Issue number | 8 |
DOIs | |
Publication status | Published - 30 Jul 2002 |