Riesgo de enfermedad cardiovascular en pacientes con infección VIH en tratamiento antirretroviral

Translated title of the contribution: Risk of cardiovascular disease in patients with HIV infection undergoing antiretroviral therapy

V. Estrada*, P. Domingo, I. Suarez-Lozano, F. Gutiérrez, H. Knobel, R. Palacios, A. Antela, J. R. Blanco, E. Refoyo

*Corresponding author for this work

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Abstract

Background: The increased survival of patients with HIV infection thanks to antiretroviral therapy (ART) is accompanied by a higher rate of cardiovascular disease (CVD). We analysed the prevalence of the cardiovascular risk factors (CRFs) and estimated the risk of CVD in a cohort of patients with HIV in Spain. Methods: We conducted a cross-sectional, observational study of CRFs in the Spanish VACH cohort of patients with HIV who undergo ART. Results: The study assessed 15,559 patients with HIV (76% men; mean age, 46 years). Some 3.7% had experienced at least 1 CVD event. The prevalence of CRFs was high (hyperlipidaemia, 64%; tobacco use, 47%; arterial hypertension, 22%; and diabetes, 16%). According to the Framingham scale, 10.9% of the patients presented a high CVD risk, and 28.8% presented a moderate risk. Of the patients with a high CVD risk, 49% took protease inhibitors and 43% took abacavir. Fifty-three percent of the patients diagnosed with arterial hypertension took antihypertensive drugs, and 2.6% of the patients with diabetes took antidiabetic agents. Conclusions: Classical CRFs are common in patients with HIV undergoing ART in Spain, and a large proportion of them have a moderate-high risk of CVD. Therefore, controlling the modifiable CRFs in patients with HIV should be improved, and the use of drugs with a better cardiovascular risk profile should be assessed.

Translated title of the contributionRisk of cardiovascular disease in patients with HIV infection undergoing antiretroviral therapy
Original languageSpanish
Pages (from-to)149-154
Number of pages6
JournalRevista Clinica Espanola
Volume220
Issue number3
DOIs
Publication statusPublished - Apr 2020

Fingerprint Dive into the research topics of 'Risk of cardiovascular disease in patients with HIV infection undergoing antiretroviral therapy'. Together they form a unique fingerprint.

Cite this