TY - JOUR
T1 - Risk Factors of Mortality from All Asbestos-Related Diseases: A Competing Risk Analysis
AU - Abós-Herràndiz, Rafael
AU - Rodriguez-Blanco, Teresa
AU - Garcia-Allas, Isabel
AU - Rosell-Murphy, Isabel Magdalena
AU - Albertí-Casas, Constança
AU - Tarrés, Josep
AU - Krier-Günther, Illona
AU - Martinez-Artés, Xavier
AU - Orriols, Ramon
AU - Grimau-Malet, Isidre
AU - Canela-Soler, Jaume
PY - 2017/1/1
Y1 - 2017/1/1
N2 - © 2017 Rafael Abós-Herràndiz et al. Background. The mortality from all malignant and nonmalignant asbestos-related diseases remains unknown. The authors assessed the incidence and risk factors for all asbestos-related deaths. Methods. The sample included 544 patients from an asbestos-exposed community in the area of Barcelona (Spain), between Jan 1, 1970, and Dec 31, 2006. Competing risk regression through a subdistribution hazard analysis was used to estimate risk factors for the outcomes. Results. Asbestos-related deaths were observed in 167 (30.7%) patients and 57.5% of these deaths were caused by some type of mesothelioma. The incidence rate after diagnosis was 3,600 per 100,000 person-years. In 7.5% of patients death was non-asbestos-related, while pleural and peritoneal mesothelioma were identified in 87 (16.0%) and 18 (3.3%) patients, respectively. Conclusions. Age, sex, household exposure, cumulative nonmalignant asbestos-related disease, and single malignant pathology were identified as risk factors for asbestos-related death. These findings suggest the need to develop a preventive approach to the community and to improve the clinical follow-up process of these patients.
AB - © 2017 Rafael Abós-Herràndiz et al. Background. The mortality from all malignant and nonmalignant asbestos-related diseases remains unknown. The authors assessed the incidence and risk factors for all asbestos-related deaths. Methods. The sample included 544 patients from an asbestos-exposed community in the area of Barcelona (Spain), between Jan 1, 1970, and Dec 31, 2006. Competing risk regression through a subdistribution hazard analysis was used to estimate risk factors for the outcomes. Results. Asbestos-related deaths were observed in 167 (30.7%) patients and 57.5% of these deaths were caused by some type of mesothelioma. The incidence rate after diagnosis was 3,600 per 100,000 person-years. In 7.5% of patients death was non-asbestos-related, while pleural and peritoneal mesothelioma were identified in 87 (16.0%) and 18 (3.3%) patients, respectively. Conclusions. Age, sex, household exposure, cumulative nonmalignant asbestos-related disease, and single malignant pathology were identified as risk factors for asbestos-related death. These findings suggest the need to develop a preventive approach to the community and to improve the clinical follow-up process of these patients.
U2 - 10.1155/2017/9015914
DO - 10.1155/2017/9015914
M3 - Article
VL - 2017
JO - Canadian Respiratory Journal
JF - Canadian Respiratory Journal
SN - 1198-2241
M1 - 9015914
ER -