Risk Factors of Mortality from All Asbestos-Related Diseases: A Competing Risk Analysis

Rafael Abós-Herràndiz, Teresa Rodriguez-Blanco, Isabel Garcia-Allas, Isabel Magdalena Rosell-Murphy, Constança Albertí-Casas, Josep Tarrés, Illona Krier-Günther, Xavier Martinez-Artés, Ramon Orriols, Isidre Grimau-Malet, Jaume Canela-Soler

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    3 Citations (Scopus)

    Abstract

    © 2017 Rafael Abós-Herràndiz et al. Background. The mortality from all malignant and nonmalignant asbestos-related diseases remains unknown. The authors assessed the incidence and risk factors for all asbestos-related deaths. Methods. The sample included 544 patients from an asbestos-exposed community in the area of Barcelona (Spain), between Jan 1, 1970, and Dec 31, 2006. Competing risk regression through a subdistribution hazard analysis was used to estimate risk factors for the outcomes. Results. Asbestos-related deaths were observed in 167 (30.7%) patients and 57.5% of these deaths were caused by some type of mesothelioma. The incidence rate after diagnosis was 3,600 per 100,000 person-years. In 7.5% of patients death was non-asbestos-related, while pleural and peritoneal mesothelioma were identified in 87 (16.0%) and 18 (3.3%) patients, respectively. Conclusions. Age, sex, household exposure, cumulative nonmalignant asbestos-related disease, and single malignant pathology were identified as risk factors for asbestos-related death. These findings suggest the need to develop a preventive approach to the community and to improve the clinical follow-up process of these patients.
    Original languageEnglish
    Article number9015914
    JournalCanadian Respiratory Journal
    Volume2017
    DOIs
    Publication statusPublished - 1 Jan 2017

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