Rhythmic oscillating complex: Characterization, induction, and relationship to MMC in chickens

M. Jimenez, V. Martinez, A. Rodriguez-Membrilla, A. Rodriguez-Sinovas, E. Gonalons, P. Vergara

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Abstract

Migrating myoelectrical complexes (MMCs) and rhythmic oscillating complexes (ROCs) have been investigated in chickens prepared for electromyography. Animals were chronically implanted with electrodes in stomach, duodenum, jejunum, ileum, ceca, and rectum. MMCs showing phases I- III were found in the jejunum and ileum both in fed and fasted states. Repetitive spike bursts were recorded in the duodenum (0.5-1/h), disrupting the gastroduodenal coordination and preceding a phase III in the jejunum. ROCs appeared spontaneously in fasted animals and in 75% of the recordings during the dark period. Four consecutive intestinal myoelectrical patterns have been described during a ROC. Briefly, they consisted in series of high- speed propagated aborad contractions of great amplitude that progressively changed into others of orad direction. In relation to the MMC, the ROC pattern appeared just after a phase III reached the distal ileum, and a pattern of duodenal repetitive spike bursts, followed by a migrating phase III in the jejunum, started at the duodenum after a ROC. No myoelectrical changes were recorded in cecorectal activity during ROC. Vagotomized animals showed the ROC pattern. Neither apomorphine (5-100 μg/kg iv) nor cholecystokinin (10-9 mol/kg iv) induced ROCs. Naloxone (5 x 10-7 mol/kg iv) and atropine (0.1 mg/kg iv) induced isolated orad contractions. Myoelectrical and functional similarities can be found between retrograde giant contractions, described in mammals, and ROCs. However, they differ in their origin and mechanism of induction.
Original languageEnglish
JournalAmerican Journal of Physiology - Gastrointestinal and Liver Physiology
Volume266
Issue number4 29-4
Publication statusPublished - 1 Jan 1994

Keywords

  • duodenogastric reflux
  • gastrointestinal motility
  • migrating myoelectric complex
  • retrograde giant contraction

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