Retrospective study on swine Torque teno virus genogroups 1 and 2 infection from 1985 to 2005 in Spain

Joaquim Segalés, Laura Martínez-Guinó, Martí Cortey, Nuria Navarro, Eva Huerta, Marina Sibila, Joan Pujols, Tuija Kekarainen

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86 Citations (Scopus)

Abstract

A retrospective study to detect evidence of swine Torque teno virus (TTV) genogroups 1 and 2 infection in sera of pigs from the Spanish livestock between years 1985 and 2005 was carried out by means of PCR. Also, the molecular evolution of TTV genogroups 1 and 2 during the 20-year period studied using a 250-base sequence of the non-coding region of the viral genome was assessed. Both TTV genogroup genomes were found in pig sera from the first year of study. Taking into account the whole study period, 113 out of 162 animals (69.8%) were infected with one or the other genogroup, while 38 out of 162 pigs (23.5%) were co-infected with both genogroups. Moreover, TTV genogroup 2 (90 out of 162, 55.6%) was significantly more prevalent than genogroup 1 (54 out of 162, 33.3%). The non-coding region of swine TTV genome sequenced showed its adequacy as a molecular marker in swine TTV. This study represents the earliest evidence of TTV infection in pigs to date, 14 years before the initial description of this virus. Moreover, this is also the earliest evidence of TTV infection in any species. © 2008 Elsevier B.V. All rights reserved.
Original languageEnglish
Pages (from-to)199-207
JournalVeterinary Microbiology
Volume134
DOIs
Publication statusPublished - 2 Mar 2009

Keywords

  • Evolution
  • Genogroup
  • Phylogeny
  • Pig
  • Retrospective
  • Torque teno virus (TTV)

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