TY - JOUR
T1 - RENEB/EURADOS field exercise 2019
T2 - robust dose estimation under outdoor conditions based on the dicentric chromosome assay
AU - Endesfelder, David
AU - Oestreicher, Ursula
AU - Kulka, Ulrike
AU - Ainsbury, Elizabeth A
AU - Moquet, Jayne
AU - Barnard, Stephen
AU - Gregoire, Eric
AU - Martinez, Juan S
AU - Trompier, François
AU - Ristic, Yoann
AU - Woda, Clemens
AU - Waldner, Lovisa
AU - Beinke, Christina
AU - Vral, Anne
AU - Barquinero, Joan-Francesc
AU - Hernandez, Alfredo
AU - Sommer, Sylwester
AU - Lumniczky, Katalin
AU - Hargitai, Rita
AU - Montoro, Alegría
AU - Milic, Mirta
AU - Monteiro Gil, Octávia
AU - Valente, Marco
AU - Bobyk, Laure
AU - Sevriukova, Olga
AU - Sabatier, Laure
AU - Prieto, María Jesús
AU - Moreno Domene, Mercedes
AU - Testa, Antonella
AU - Patrono, Clarice
AU - Terzoudi, Georgia
AU - Triantopoulou, Sotiria
AU - Histova, Rositsa
AU - Wojcik, Andrzej
N1 - Publisher Copyright:
© Copyright © 2021 The Author(s). Published with license by Taylor & Francis Group, LLC.
PY - 2021/9/2
Y1 - 2021/9/2
N2 - Purpose Biological and/or physical assays for retrospective dosimetry are valuable tools to recover the exposure situation and to aid medical decision making. To further validate and improve such biological and physical assays, in 2019, EURADOS Working Group 10 and RENEB performed a field exercise in Lund, Sweden, to simulate various real-life exposure scenarios. Materials and methods For the dicentric chromosome assay (DCA), blood tubes were located at anthropomorphic phantoms positioned in different geometries and were irradiated with a 1.36 TBq Ir-192-source. For each exposure condition, dose estimates were provided by at least one laboratory and for four conditions by 17 participating RENEB laboratories. Three radio-photoluminescence glass dosimeters were placed at each tube to assess reference doses. Results The DCA results were homogeneous between participants and matched well with the reference doses (>= 95% of estimates within +/- 0.5 Gy of the reference). For samples close to the source systematic underestimation could be corrected by accounting for exposure time. Heterogeneity within and between tubes was detected for reference doses as well as for DCA doses estimates. Conclusions The participants were able to successfully estimate the doses and to provide important information on the exposure scenarios under conditions closely resembling a real-life situation.
AB - Purpose Biological and/or physical assays for retrospective dosimetry are valuable tools to recover the exposure situation and to aid medical decision making. To further validate and improve such biological and physical assays, in 2019, EURADOS Working Group 10 and RENEB performed a field exercise in Lund, Sweden, to simulate various real-life exposure scenarios. Materials and methods For the dicentric chromosome assay (DCA), blood tubes were located at anthropomorphic phantoms positioned in different geometries and were irradiated with a 1.36 TBq Ir-192-source. For each exposure condition, dose estimates were provided by at least one laboratory and for four conditions by 17 participating RENEB laboratories. Three radio-photoluminescence glass dosimeters were placed at each tube to assess reference doses. Results The DCA results were homogeneous between participants and matched well with the reference doses (>= 95% of estimates within +/- 0.5 Gy of the reference). For samples close to the source systematic underestimation could be corrected by accounting for exposure time. Heterogeneity within and between tubes was detected for reference doses as well as for DCA doses estimates. Conclusions The participants were able to successfully estimate the doses and to provide important information on the exposure scenarios under conditions closely resembling a real-life situation.
KW - biological dosimetry
KW - Dicentric chromosome
KW - EURADOS
KW - inter-laboratory comparison
KW - RENEB
UR - http://www.scopus.com/inward/record.url?scp=85109840839&partnerID=8YFLogxK
U2 - 10.1080/09553002.2021.1941380
DO - 10.1080/09553002.2021.1941380
M3 - Article
C2 - 34138666
SN - 0955-3002
VL - 97
SP - 1
EP - 18
JO - International Journal of Radiation Biology
JF - International Journal of Radiation Biology
IS - 9
ER -