Renal angiomyolipoma: Presentation, treatment and results of 20 cases

J. E. Bestard Vallejo, E. Trilla Herrera, A. Celma Domenech, M. Pérez Lafuente, I. de Torres Ramírez, J. Morote Robles

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Abstract

Introduction: Renal angiomyolipoma is a benign tumour, but its spontaneous rupture may become threatening for patient's live. Both surgery and selective arterial embolization are accepted treatments for this lesion. Objectives: Analyze renal angyolipoma treated in our center, their clinical outcome and treatment purposed in each case. Material and Methods: We retrospectively analyse 20 cases of patients with renal angiomyolipoma treated in our centre from March 1996 to March 2006. We describe tumour characteristics, treatment followed and results obtained. Results: Patients suffering from tuberous sclerosis (20%) showed multiple bilateral tumours, with size similar to the rest of patients. Diagnosis of tuberous sclerosis: was the only factor attached to spontaneous rupture of those lesions. Four of 9 emergency embolized patients (44.4%) required from second treatment because of recurrent haemorrhage, and 4 of the 16 embolization episodes (25%) presented post-embolization syndrome, both with no predicting factors attached. Reduction of less than one third of the inicial diamete was observed in 58.4% of embolized tumours, which used to be multiple, bilateral and of size larger to the rest. No significative differences were observed in plasmatic creatinine after and before treatments. Conclusions: Renal angiomyolipoma may behave in an aggressive way in patients with tuberous sclerosis. No predicting factors of recurrent haemorrhage or post-embolization syndrome were observed. Both surgery and arterial embolization have proved not to compromise renal function in treated patients.
Original languageEnglish
Pages (from-to)307-315
JournalActas Urologicas Espanolas
Volume32
Issue number3
DOIs
Publication statusPublished - 1 Jan 2008

Keywords

  • Renal angiomyohponia
  • Selective embolization
  • Tuberous sclerosis complex

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    Bestard Vallejo, J. E., Trilla Herrera, E., Celma Domenech, A., Pérez Lafuente, M., de Torres Ramírez, I., & Morote Robles, J. (2008). Renal angiomyolipoma: Presentation, treatment and results of 20 cases. Actas Urologicas Espanolas, 32(3), 307-315. https://doi.org/10.1016/S0210-4806(08)73835-X