Relationships of hepatic and pancreatic biomarkers with the cholestatic syndrome and tumor stage in pancreatic cancer

Miquel Porta, José Pumarega, Luisa Guarner, Núria Malats, Ricard Solà, Francisco X. Real

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Abstract

We analyzed relationships of hepatic and pancreatic biomarkers with the cholestatic syndrome and tumor stage in exocrine pancreatic cancer (N = 183). Information on laboratory tests and on signs and symptoms was obtained from medical records and patient interviews. Bilirubin, aspartate aminotransferase (AST), γ-glutamyltransferase (GGT) and alkaline phosphatase were lower in tumor stage IV. The association was due to the relationship between cholestatic syndrome and earlier presentation of patients. There was no association between hepatic biomarkers and stage when adjusting by cholestatic syndrome. Relationships of hepatic and pancreatic biomarkers with pancreatic symptoms and tumor stage must be controlled in "-omics" and other studies using biomarkers. © 2012 Informa UK, Ltd.
Original languageEnglish
Pages (from-to)557-565
JournalBiomarkers
Volume17
Issue number6
DOIs
Publication statusPublished - 1 Sep 2012

Keywords

  • [Non-MeSH terms]: semiology
  • AST
  • Blood draw
  • Choluria
  • Glycemia
  • Hypocholia
  • Jaundice
  • Regression coefficient
  • Symptoms

Fingerprint Dive into the research topics of 'Relationships of hepatic and pancreatic biomarkers with the cholestatic syndrome and tumor stage in pancreatic cancer'. Together they form a unique fingerprint.

  • Cite this