Background: Enlargement of renal size plays an important role in the development of hypertension in patients with autosomal dominant polycystic kidney disease (ADPKD) and normal renal function. Methods: A 24h blood pressure monitoring (ABPM) and a renal ecography have been performed in 37 patients with ADPKD and estimated glomerular filtration rate >60 ml/min/1,73 m2 to study the relationship between renal size and an altered blood pressure profile in prehypertension stages. Results: 13 patients had normal blood pressure, 11 were diagnosed of masked hypertension, 4 had white coat hypertension and 9 had hypertension. We have found in the normotensive group with a dipper blood pressure profile a positive and statistically significant relationship between renal size and diastolic blood pressure variability. Conclusions: ABPM helps to make an early diagnosis of hypertension and to identify those patients with masked hypertension. This study suggests a relationship between renal size and a blood pressure profile linked to a major cardiovasular risk in normotensive patients with ADPKD. © 2010 Revista Nefrología. Órgano Oficial de la Sociedad Española de Nefrología.
|Publication status||Published - 1 Jan 2010|
- Ambulatory monitoring of blood pressure
- Autosomal dominant polycystic kidney disease
- Blood pressure profile
- Blood pressure variability
- Renal size
Sans Atxer, L., Roca-Cusachs, A., Torra, R., Calero, F., Arias, P., Ballarin, J., & Fernández-Llama, P. (2010). Relationship between kidney size and blood pressure profile in patients with autosomal dominant polycystic kidney disease without renal failure. Nefrologia, 30(5), 567-572. https://doi.org/10.3265/Nefrologia.pre2010.May.10418