Regeneration and functional recovery following peripheral nerve injury

Francisco J. Rodríguez; Antoni Valero-Cabré; Xavier Navarro

doi:10.1016/j.ddmod.2004.09.008

Regeneration and functional recovery following peripheral nerve injury

Francisco J. Rodríguez, Antoni Valero-Cabré, Xavier Navarro

Department of Cellular Biology, Physiology and Immunology

Research output: Contribution to journal › Review article › Research › peer-review

73 Citations (Scopus)

Abstract

Peripheral nerve injuries result in loss of neural control in denervated segments of the body, and severe disabilities for the patients. Nerve regeneration usually does not allow for adequate target reinnervation and functional restitution. Neuronal response and axonal regeneration imply a complex interaction of cell types and changes in the expression of many molecules. Many experimental models have been used to gain knowledge on nerve regeneration and to develop strategies to promote recovery. © 2004 Elsevier Ltd. All rights reserved.

Original language	English
Pages (from-to)	177-185
Journal	Drug Discovery Today: Disease Models
Volume	1
Issue number	2
DOIs	https://doi.org/10.1016/j.ddmod.2004.09.008
Publication status	Published - 1 Jan 2004

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title = "Regeneration and functional recovery following peripheral nerve injury",

abstract = "Peripheral nerve injuries result in loss of neural control in denervated segments of the body, and severe disabilities for the patients. Nerve regeneration usually does not allow for adequate target reinnervation and functional restitution. Neuronal response and axonal regeneration imply a complex interaction of cell types and changes in the expression of many molecules. Many experimental models have been used to gain knowledge on nerve regeneration and to develop strategies to promote recovery. {\textcopyright} 2004 Elsevier Ltd. All rights reserved.",

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N2 - Peripheral nerve injuries result in loss of neural control in denervated segments of the body, and severe disabilities for the patients. Nerve regeneration usually does not allow for adequate target reinnervation and functional restitution. Neuronal response and axonal regeneration imply a complex interaction of cell types and changes in the expression of many molecules. Many experimental models have been used to gain knowledge on nerve regeneration and to develop strategies to promote recovery. © 2004 Elsevier Ltd. All rights reserved.

AB - Peripheral nerve injuries result in loss of neural control in denervated segments of the body, and severe disabilities for the patients. Nerve regeneration usually does not allow for adequate target reinnervation and functional restitution. Neuronal response and axonal regeneration imply a complex interaction of cell types and changes in the expression of many molecules. Many experimental models have been used to gain knowledge on nerve regeneration and to develop strategies to promote recovery. © 2004 Elsevier Ltd. All rights reserved.

U2 - 10.1016/j.ddmod.2004.09.008

DO - 10.1016/j.ddmod.2004.09.008

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JO - Drug Discovery Today: Disease Models

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