Reduction of piperidinoisoxazolidines: Competitive cyclisation to indolizidines or epoxides

Ramón Alibés, Félix Busqué, Pedro De March, Marta Figueredo, Josep Font

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Abstract

In the reduction of polysubstituted piperidinoisoxazolidines, we have observed two competitive cyclisation pathways, leading to either indolizidines or epoxides. The yields of indolizidines can be optimised by an appropriate choice of the reducing agent and through a careful control of the work-up conditions.
Original languageEnglish
Pages (from-to)11581-11588
JournalTetrahedron
Volume54
Issue number38
DOIs
Publication statusPublished - 17 Sep 1998

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