Red blood cell fatty acids in multiple sclerosis.

X. Navarro; R. Segura

doi:10.1111/j.1600-0404.1989.tb03706.x

Red blood cell fatty acids in multiple sclerosis.

X. Navarro, R. Segura

Research output: Contribution to journal › Article › Research

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Abstract

The fatty acid (FA) composition of each phospholipid constituent of the red blood cells (RBC) was analyzed, by thin‐layer and gas chromatography techniques, in 61 multiple sclerosis (MS) patients and 61 normal subjects, in whom the plasma lipid FA composition had previously been studied. The MS patients showed a significant decrease in the proportions of linoleic and arachidonic acids in most phospholipids, with a compensatory increase of saturated FA. Correlations between FA percentages in plasma and cell lipids demonstrated abnormalities in the MS patients, suggestive of a disturbance in the exchange between these compartments. The alterations reported in plasma and RBC in the MS patients are consistent with a relative deficiency of essential FA Copyright © 1989, Wiley Blackwell. All rights reserved

Original language	English
Pages (from-to)	32-37
Journal	Acta Neurologica Scandinavica
Volume	79
Issue number	1
DOIs	https://doi.org/10.1111/j.1600-0404.1989.tb03706.x
Publication status	Published - 1 Jan 1989

Keywords

fatty acids
linoleic acid
multiple sclerosis
phospholipids
red blood cells

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10.1111/j.1600-0404.1989.tb03706.x

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title = "Red blood cell fatty acids in multiple sclerosis.",

abstract = "The fatty acid (FA) composition of each phospholipid constituent of the red blood cells (RBC) was analyzed, by thin‐layer and gas chromatography techniques, in 61 multiple sclerosis (MS) patients and 61 normal subjects, in whom the plasma lipid FA composition had previously been studied. The MS patients showed a significant decrease in the proportions of linoleic and arachidonic acids in most phospholipids, with a compensatory increase of saturated FA. Correlations between FA percentages in plasma and cell lipids demonstrated abnormalities in the MS patients, suggestive of a disturbance in the exchange between these compartments. The alterations reported in plasma and RBC in the MS patients are consistent with a relative deficiency of essential FA Copyright {\textcopyright} 1989, Wiley Blackwell. All rights reserved",

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doi = "10.1111/j.1600-0404.1989.tb03706.x",

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AU - Segura, R.

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N2 - The fatty acid (FA) composition of each phospholipid constituent of the red blood cells (RBC) was analyzed, by thin‐layer and gas chromatography techniques, in 61 multiple sclerosis (MS) patients and 61 normal subjects, in whom the plasma lipid FA composition had previously been studied. The MS patients showed a significant decrease in the proportions of linoleic and arachidonic acids in most phospholipids, with a compensatory increase of saturated FA. Correlations between FA percentages in plasma and cell lipids demonstrated abnormalities in the MS patients, suggestive of a disturbance in the exchange between these compartments. The alterations reported in plasma and RBC in the MS patients are consistent with a relative deficiency of essential FA Copyright © 1989, Wiley Blackwell. All rights reserved

AB - The fatty acid (FA) composition of each phospholipid constituent of the red blood cells (RBC) was analyzed, by thin‐layer and gas chromatography techniques, in 61 multiple sclerosis (MS) patients and 61 normal subjects, in whom the plasma lipid FA composition had previously been studied. The MS patients showed a significant decrease in the proportions of linoleic and arachidonic acids in most phospholipids, with a compensatory increase of saturated FA. Correlations between FA percentages in plasma and cell lipids demonstrated abnormalities in the MS patients, suggestive of a disturbance in the exchange between these compartments. The alterations reported in plasma and RBC in the MS patients are consistent with a relative deficiency of essential FA Copyright © 1989, Wiley Blackwell. All rights reserved

KW - fatty acids

KW - linoleic acid

KW - multiple sclerosis

KW - phospholipids

KW - red blood cells

U2 - 10.1111/j.1600-0404.1989.tb03706.x

DO - 10.1111/j.1600-0404.1989.tb03706.x

M3 - Article

SN - 0001-6314

VL - 79

SP - 32

EP - 37

JO - Acta Neurologica Scandinavica

JF - Acta Neurologica Scandinavica

IS - 1

ER -

Red blood cell fatty acids in multiple sclerosis.

Abstract

Keywords

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