Recurrent urinary tract infections

Carlos Pigrau-Serrallach

    Research output: Contribution to journalArticleResearchpeer-review

    11 Citations (Scopus)

    Abstract

    Recurrent urinary tract infections (RUTI) are a frequent clinical problem in sexually active young women, pregnant or postmenopausal women and in patients with underlying urological abnormalities. The present chapter reviews RUTI based on their classification: relapses, which usually occur early (< 1 month), are caused by the same microorganism and are associated with underlying urological abnormalities, and reinfections, which usually occur later and are caused by a new distinct microorganism (or by the same microorganism usually located in the rectum or uroepithelial cells). The pathogenesis of RUTI is reviewed and the risk factors associated with RUTI in premenopausal women (usually related to sexual activity), postmenopausal women (in whom estrogen deficiency has a significant effect on the vaginal Lactobacillusflora), and in pregnant women are discussed. Likewise, an extensive review of the distinct therapeutic strategies to prevent RUTI is provided: self-treatment of cystitis, continuous antibiotic prophylaxis, postcoital antibiotic prophylaxis, topical vaginal estrogens, Lactobacillus, cranberry juice, intravesical administration of non-virulent E. colistrains and vaccines, among others. Several diagnostic-therapeutic algorithms are included. These algorithms are based on the type of urinary infection (relapse-reinfection), on the type of patient (young, postmenopausal, or pregnant women) and on the number of episodes of RUTI.
    Original languageEnglish
    Pages (from-to)28-39
    JournalEnfermedades Infecciosas y Microbiologia Clinica
    Volume23
    Issue numberSUPPL.4
    DOIs
    Publication statusPublished - 3 Dec 2005

    Keywords

    • Antibiotic prophylaxis in recurrent urinary infections
    • Cranberries and urinary infection
    • Intravaginal lactobacillus
    • Prophylaxis
    • Recurrent urinary infections in young
    • Recurrent urinary tract infections
    • Sexually active women and postmenopausal women

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